WDR75 protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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Score

WDR75

WD repeat domain 75 (830 aa)

Predicted Functional Partners:

UTP15

0.998

WDR43

0.998

PWP2

0.998

HEATR1

0.998

NOP14

0.996

BMS1

0.995

PDCD11

0.995

UTP6

0.994

RRP9

0.993

NOC4L

0.993

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMS1	HEATR1	ENSP00000363642	ENSP00000355541	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	0.997
BMS1	NOC4L	ENSP00000363642	ENSP00000328854	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	nucleolar complex associated 4 homolog (S. cerevisiae)	0.985
BMS1	NOP14	ENSP00000363642	ENSP00000315674	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.999
BMS1	PDCD11	ENSP00000363642	ENSP00000358812	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA	0.989
BMS1	PWP2	ENSP00000363642	ENSP00000291576	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	PWP2 periodic tryptophan protein homolog (yeast)	0.998
BMS1	RRP9	ENSP00000363642	ENSP00000232888	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA	0.996
BMS1	UTP15	ENSP00000363642	ENSP00000296792	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)	0.974
BMS1	UTP6	ENSP00000363642	ENSP00000261708	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	UTP6, small subunit (SSU) processome component, homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)	0.991
BMS1	WDR43	ENSP00000363642	ENSP00000384302	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	WD repeat domain 43	0.895
BMS1	WDR75	ENSP00000363642	ENSP00000314193	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	WD repeat domain 75	0.995
HEATR1	BMS1	ENSP00000355541	ENSP00000363642	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity)	0.997
HEATR1	NOC4L	ENSP00000355541	ENSP00000328854	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	nucleolar complex associated 4 homolog (S. cerevisiae)	0.996
HEATR1	NOP14	ENSP00000355541	ENSP00000315674	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.994
HEATR1	PDCD11	ENSP00000355541	ENSP00000358812	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA	0.994
HEATR1	PWP2	ENSP00000355541	ENSP00000291576	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	PWP2 periodic tryptophan protein homolog (yeast)	0.999
HEATR1	RRP9	ENSP00000355541	ENSP00000232888	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA	0.990
HEATR1	UTP15	ENSP00000355541	ENSP00000296792	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)	0.997
HEATR1	UTP6	ENSP00000355541	ENSP00000261708	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	UTP6, small subunit (SSU) processome component, homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)	0.985
HEATR1	WDR43	ENSP00000355541	ENSP00000384302	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	WD repeat domain 43	0.997
HEATR1	WDR75	ENSP00000355541	ENSP00000314193	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	WD repeat domain 75	0.998

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