node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLHC1 | CLTA | ENSP00000384869 | ENSP00000242285 | clathrin heavy chain linker domain containing 1 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | 0.826 |
CLHC1 | CLTB | ENSP00000384869 | ENSP00000309415 | clathrin heavy chain linker domain containing 1 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | 0.826 |
CLHC1 | GAK | ENSP00000384869 | ENSP00000314499 | clathrin heavy chain linker domain containing 1 | cyclin G associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 | 0.920 |
CLHC1 | HIP1R | ENSP00000384869 | ENSP00000253083 | clathrin heavy chain linker domain containing 1 | huntingtin interacting protein 1 related; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis | 0.552 |
CLTA | CLHC1 | ENSP00000242285 | ENSP00000384869 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin heavy chain linker domain containing 1 | 0.826 |
CLTA | CLTB | ENSP00000242285 | ENSP00000309415 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | 0.903 |
CLTA | CLTC | ENSP00000242285 | ENSP00000269122 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin, heavy chain (Hc); Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network | 0.998 |
CLTA | CLTCL1 | ENSP00000242285 | ENSP00000445677 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin, heavy chain-like 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity) | 0.961 |
CLTA | GAK | ENSP00000242285 | ENSP00000314499 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | cyclin G associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 | 0.953 |
CLTA | HIP1R | ENSP00000242285 | ENSP00000253083 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | huntingtin interacting protein 1 related; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis | 0.917 |
CLTA | HSPA8 | ENSP00000242285 | ENSP00000227378 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | 0.653 |
CLTA | UBC | ENSP00000242285 | ENSP00000344818 | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | ubiquitin C | 0.811 |
CLTB | CLHC1 | ENSP00000309415 | ENSP00000384869 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin heavy chain linker domain containing 1 | 0.826 |
CLTB | CLTA | ENSP00000309415 | ENSP00000242285 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | 0.903 |
CLTB | CLTC | ENSP00000309415 | ENSP00000269122 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin, heavy chain (Hc); Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network | 0.991 |
CLTB | CLTCL1 | ENSP00000309415 | ENSP00000445677 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | clathrin, heavy chain-like 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity) | 0.948 |
CLTB | GAK | ENSP00000309415 | ENSP00000314499 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | cyclin G associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 | 0.955 |
CLTB | HIP1R | ENSP00000309415 | ENSP00000253083 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | huntingtin interacting protein 1 related; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis | 0.985 |
CLTB | UBC | ENSP00000309415 | ENSP00000344818 | clathrin, light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | ubiquitin C | 0.755 |
CLTC | CLTA | ENSP00000269122 | ENSP00000242285 | clathrin, heavy chain (Hc); Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network | clathrin, light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles | 0.998 |