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STRINGSTRING
ELMOD1 ELMOD1 SLC35F2 SLC35F2 RFC5 RFC5 ERCC5 ERCC5 MARC1 MARC1 KDELC2 KDELC2 YEATS2 YEATS2 C11orf65 C11orf65 TMEM40 TMEM40 EXPH5 EXPH5 TNFAIP8L3 TNFAIP8L3
"KDELC2" - KDEL in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDELC2KDEL (Lys-Asp-Glu-Leu) containing 2 (507 aa)    
Predicted Functional Partners:
C11orf65
chromosome 11 open reading frame 65 (313 aa)
            score_image   0.810
ELMOD1
ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (334 aa)
            score_image   0.765
RFC5
replication factor C (activator 1) 5, 36.5kDa; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1 (340 aa)
            score_image   0.591
ERCC5
excision repair cross-complementing rodent repair deficiency, complementation group 5; Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3’incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too (1186 aa)
            score_image   0.583
YEATS2
YEATS domain containing 2; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (1422 aa)
            score_image   0.570
SLC35F2
solute carrier family 35, member F2; Putative solute transporter (Potential) (374 aa)
            score_image   0.550
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3 (292 aa)
            score_image   0.501
TMEM40
transmembrane protein 40 (233 aa)
            score_image   0.501
EXPH5
exophilin 5; May act as Rab effector protein and play a role in vesicle trafficking (1989 aa)
            score_image   0.470
MARC1
mitochondrial amidoxime reducing component 1 (337 aa)
            score_image   0.464
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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