node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGPHD1 | CHRNA3 | ENSP00000373640 | ENSP00000315602 | aminoglycoside phosphotransferase domain containing 1; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.824 |
AGPHD1 | CHRNA4 | ENSP00000373640 | ENSP00000359285 | aminoglycoside phosphotransferase domain containing 1; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine | cholinergic receptor, nicotinic, alpha 4 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions | 0.502 |
AGPHD1 | CHRNA5 | ENSP00000373640 | ENSP00000299565 | aminoglycoside phosphotransferase domain containing 1; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine | cholinergic receptor, nicotinic, alpha 5 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.822 |
AGPHD1 | CHRNB4 | ENSP00000373640 | ENSP00000261751 | aminoglycoside phosphotransferase domain containing 1; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine | cholinergic receptor, nicotinic, beta 4 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.730 |
AGPHD1 | PSMA4 | ENSP00000373640 | ENSP00000044462 | aminoglycoside phosphotransferase domain containing 1; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine | proteasome (prosome, macropain) subunit, alpha type, 4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) | 0.751 |
CHRNA2 | CHRNA3 | ENSP00000385026 | ENSP00000315602 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.902 |
CHRNA2 | CHRNA4 | ENSP00000385026 | ENSP00000359285 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 4 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions | 0.903 |
CHRNA2 | CHRNA5 | ENSP00000385026 | ENSP00000299565 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 5 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.748 |
CHRNA2 | CHRNA7 | ENSP00000385026 | ENSP00000407546 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 7 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin | 0.910 |
CHRNA2 | CHRNB2 | ENSP00000385026 | ENSP00000357461 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, beta 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions | 0.958 |
CHRNA2 | CHRNB3 | ENSP00000385026 | ENSP00000289957 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, beta 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.744 |
CHRNA2 | CHRNB4 | ENSP00000385026 | ENSP00000261751 | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, beta 4 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.957 |
CHRNA3 | AGPHD1 | ENSP00000315602 | ENSP00000373640 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | aminoglycoside phosphotransferase domain containing 1; Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine | 0.824 |
CHRNA3 | CHRNA2 | ENSP00000315602 | ENSP00000385026 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.902 |
CHRNA3 | CHRNA4 | ENSP00000315602 | ENSP00000359285 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 4 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions | 0.904 |
CHRNA3 | CHRNA5 | ENSP00000315602 | ENSP00000299565 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 5 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.766 |
CHRNA3 | CHRNA7 | ENSP00000315602 | ENSP00000407546 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, alpha 7 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin | 0.908 |
CHRNA3 | CHRNB2 | ENSP00000315602 | ENSP00000357461 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, beta 2 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions | 0.905 |
CHRNA3 | CHRNB3 | ENSP00000315602 | ENSP00000289957 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, beta 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.749 |
CHRNA3 | CHRNB4 | ENSP00000315602 | ENSP00000261751 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | cholinergic receptor, nicotinic, beta 4 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.958 |