RNF32 protein (Homo sapiens) - STRING network view

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RNF32

ring finger protein 32; May play a role in sperm formation (362 aa)

Predicted Functional Partners:

C7orf13

0.910

NOM1

0.802

LMBR1

0.784

PROSAPIP1

0.672

HSD17B14

0.648

PRKRA

0.629

LMBR1L

0.587

MNX1

0.546

MKRN3

0.496

TRIM23

0.496

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7orf13	NOM1	ENSP00000331784	ENSP00000275820	chromosome 7 open reading frame 13	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	0.519
C7orf13	RNF32	ENSP00000331784	ENSP00000315950	chromosome 7 open reading frame 13	ring finger protein 32; May play a role in sperm formation	0.910
HSD17B14	PRKRA	ENSP00000263278	ENSP00000318176	hydroxysteroid (17-beta) dehydrogenase 14; Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro)	protein kinase, interferon-inducible double stranded RNA dependent activator; Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post- transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at ’Lys-386’ at ’Ser-392’ respectively and enhances its activity in [...]	0.647
HSD17B14	RNF32	ENSP00000263278	ENSP00000315950	hydroxysteroid (17-beta) dehydrogenase 14; Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro)	ring finger protein 32; May play a role in sperm formation	0.648
LMBR1	NOM1	ENSP00000326604	ENSP00000275820	limb region 1 homolog (mouse); Putative membrane receptor	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	0.635
LMBR1	RNF32	ENSP00000326604	ENSP00000315950	limb region 1 homolog (mouse); Putative membrane receptor	ring finger protein 32; May play a role in sperm formation	0.784
LMBR1L	RNF32	ENSP00000267102	ENSP00000315950	limb region 1 homolog (mouse)-like; Probable LCN1 receptor. May mediate LCN1 endocytosis	ring finger protein 32; May play a role in sperm formation	0.587
MKRN3	RNF32	ENSP00000313881	ENSP00000315950	makorin ring finger protein 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity)	ring finger protein 32; May play a role in sperm formation	0.496
MKRN3	TRIM23	ENSP00000313881	ENSP00000231524	makorin ring finger protein 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity)	tripartite motif containing 23; Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in ’Lys-63’-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit	0.461
MNX1	NOM1	ENSP00000252971	ENSP00000275820	motor neuron and pancreas homeobox 1; Putative transcription factor involved in pancreas development and function	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	0.542
MNX1	RNF32	ENSP00000252971	ENSP00000315950	motor neuron and pancreas homeobox 1; Putative transcription factor involved in pancreas development and function	ring finger protein 32; May play a role in sperm formation	0.546
NOM1	C7orf13	ENSP00000275820	ENSP00000331784	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	chromosome 7 open reading frame 13	0.519
NOM1	LMBR1	ENSP00000275820	ENSP00000326604	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	limb region 1 homolog (mouse); Putative membrane receptor	0.635
NOM1	MNX1	ENSP00000275820	ENSP00000252971	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	motor neuron and pancreas homeobox 1; Putative transcription factor involved in pancreas development and function	0.542
NOM1	RNF32	ENSP00000275820	ENSP00000315950	nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus	ring finger protein 32; May play a role in sperm formation	0.802
PRKRA	HSD17B14	ENSP00000318176	ENSP00000263278	protein kinase, interferon-inducible double stranded RNA dependent activator; Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post- transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at ’Lys-386’ at ’Ser-392’ respectively and enhances its activity in [...]	hydroxysteroid (17-beta) dehydrogenase 14; Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro)	0.647
PRKRA	RNF32	ENSP00000318176	ENSP00000315950	protein kinase, interferon-inducible double stranded RNA dependent activator; Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post- transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at ’Lys-386’ at ’Ser-392’ respectively and enhances its activity in [...]	ring finger protein 32; May play a role in sperm formation	0.629
PROSAPIP1	RNF32	ENSP00000332123	ENSP00000315950	ProSAP-interacting protein 1	ring finger protein 32; May play a role in sperm formation	0.672
RNF32	C7orf13	ENSP00000315950	ENSP00000331784	ring finger protein 32; May play a role in sperm formation	chromosome 7 open reading frame 13	0.910
RNF32	HSD17B14	ENSP00000315950	ENSP00000263278	ring finger protein 32; May play a role in sperm formation	hydroxysteroid (17-beta) dehydrogenase 14; Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro)	0.648

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