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STRINGSTRING
SLC25A24 SLC25A24 EMR2 EMR2 CD97 CD97 PGAP1 PGAP1 CD59 CD59 CD55 CD55 C3 C3 NDUFB7 NDUFB7 ZMPSTE24 ZMPSTE24 LCK LCK PTCD3 PTCD3
CD55 molecule, decay accelerating factor for complement (Cromer blood group) in Homo sapiens
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protein of unknown 3D structure
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CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group); This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (440 aa)    
Predicted Functional Partners:
CD97
CD97 molecule; Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity) (835 aa)
        score_image score_image score_image   0.997
C3
complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (1663 aa)
          score_image score_image   0.991
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2; Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF (823 aa)
            score_image   0.935
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (477 aa)
        score_image       0.905
CD59
CD59 molecule, complement regulatory protein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase (128 aa)
            score_image   0.901
NDUFB7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (137 aa)
        score_image       0.892
LCK
lymphocyte-specific protein tyrosine kinase (509 aa)
        score_image   score_image   0.874
PTCD3
pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation (689 aa)
        score_image       0.869
ZMPSTE24
zinc metallopeptidase STE24 homolog (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C (475 aa)
        score_image       0.821
PGAP1
post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) (922 aa)
            score_image   0.752
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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