node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACLY | DPYD | ENSP00000253792 | ENSP00000359211 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | dihydropyrimidine dehydrogenase | 0.940 |
ACLY | SLC36A1 | ENSP00000253792 | ENSP00000243389 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity) | 0.591 |
ACLY | SLC36A2 | ENSP00000253792 | ENSP00000334223 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | solute carrier family 36 (proton/amino acid symporter), member 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity) | 0.595 |
ACLY | SLC36A3 | ENSP00000253792 | ENSP00000366942 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | solute carrier family 36 (proton/amino acid symporter), member 3 | 0.591 |
ACLY | SLC36A4 | ENSP00000253792 | ENSP00000317382 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | solute carrier family 36 (proton/amino acid symporter), member 4; Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine. Inhibited by sarcosine | 0.591 |
ACLY | SLC38A7 | ENSP00000253792 | ENSP00000219320 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | solute carrier family 38, member 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine (By similarity) | 0.591 |
ACLY | SLC38A9 | ENSP00000253792 | ENSP00000316596 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.591 |
C1orf131 | SLC38A9 | ENSP00000355609 | ENSP00000316596 | chromosome 1 open reading frame 131 | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.502 |
DPYD | ACLY | ENSP00000359211 | ENSP00000253792 | dihydropyrimidine dehydrogenase | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.940 |
DPYD | SLC36A1 | ENSP00000359211 | ENSP00000243389 | dihydropyrimidine dehydrogenase | solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity) | 0.557 |
DPYD | SLC36A2 | ENSP00000359211 | ENSP00000334223 | dihydropyrimidine dehydrogenase | solute carrier family 36 (proton/amino acid symporter), member 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity) | 0.557 |
DPYD | SLC36A3 | ENSP00000359211 | ENSP00000366942 | dihydropyrimidine dehydrogenase | solute carrier family 36 (proton/amino acid symporter), member 3 | 0.557 |
DPYD | SLC36A4 | ENSP00000359211 | ENSP00000317382 | dihydropyrimidine dehydrogenase | solute carrier family 36 (proton/amino acid symporter), member 4; Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine. Inhibited by sarcosine | 0.557 |
DPYD | SLC38A7 | ENSP00000359211 | ENSP00000219320 | dihydropyrimidine dehydrogenase | solute carrier family 38, member 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine (By similarity) | 0.557 |
DPYD | SLC38A9 | ENSP00000359211 | ENSP00000316596 | dihydropyrimidine dehydrogenase | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.557 |
FAM71E1 | SLC38A9 | ENSP00000270620 | ENSP00000316596 | family with sequence similarity 71, member E1 | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.538 |
OR2L2 | SLC38A9 | ENSP00000355435 | ENSP00000316596 | olfactory receptor, family 2, subfamily L, member 2; Odorant receptor (Potential) | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.472 |
SLC36A1 | ACLY | ENSP00000243389 | ENSP00000253792 | solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity) | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.591 |
SLC36A1 | DPYD | ENSP00000243389 | ENSP00000359211 | solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity) | dihydropyrimidine dehydrogenase | 0.557 |
SLC36A1 | SLC38A7 | ENSP00000243389 | ENSP00000219320 | solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity) | solute carrier family 38, member 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine (By similarity) | 0.542 |