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STRINGSTRING
PLCXD1 PLCXD1 ARSD ARSD TRIT1 TRIT1 PPP2R3B PPP2R3B DHRSX DHRSX ASMT ASMT GTPBP6 GTPBP6 TBL1Y TBL1Y ASMTL ASMTL GTPBP4 GTPBP4 PGPEP1 PGPEP1
"GTPBP6" - GTP binding protein 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
GTPBP6GTP binding protein 6 (putative) (287 aa)    
Predicted Functional Partners:
GTPBP4
GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) (634 aa)
            score_image   0.759
DHRSX
dehydrogenase/reductase (SDR family) X-linked (330 aa)
      score_image     score_image   0.746
ASMTL
acetylserotonin O-methyltransferase-like; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity (621 aa)
            score_image   0.686
PGPEP1
pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline (209 aa)
            score_image   0.675
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1 (323 aa)
            score_image   0.674
TRIT1
tRNA isopentenyltransferase 1; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (467 aa)
score_image     score_image     score_image   0.671
TBL1Y
transducin (beta)-like 1, Y-linked; F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity) (522 aa)
            score_image   0.598
ASMT
acetylserotonin O-methyltransferase; Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5- methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity (373 aa)
            score_image   0.590
PPP2R3B
protein phosphatase 2, regulatory subunit B’’, beta; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment (575 aa)
            score_image   0.580
ARSD
arylsulfatase D (593 aa)
            score_image   0.576
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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