| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATOX1 | ATP7A | ENSP00000316854 | ENSP00000345728 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | 0.999 |
| ATOX1 | ATP7B | ENSP00000316854 | ENSP00000242839 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | ATPase, Cu++ transporting, beta polypeptide; Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile | 0.999 |
| ATOX1 | CCS | ENSP00000316854 | ENSP00000436318 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | copper chaperone for superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) | 0.833 |
| ATOX1 | COX11 | ENSP00000316854 | ENSP00000299335 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.726 |
| ATOX1 | COX17 | ENSP00000316854 | ENSP00000261070 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | 0.828 |
| ATOX1 | FKBP4 | ENSP00000316854 | ENSP00000001008 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | FK506 binding protein 4, 59kDa; Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembl [...] | 0.976 |
| ATOX1 | SLC31A1 | ENSP00000316854 | ENSP00000363329 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | solute carrier family 31 (copper transporters), member 1; High-affinity, saturable copper transporter involved in dietary copper uptake | 0.713 |
| ATOX1 | SOD1 | ENSP00000316854 | ENSP00000270142 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | superoxide dismutase 1, soluble; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) | 0.732 |
| ATOX1 | SOD3 | ENSP00000316854 | ENSP00000371554 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | superoxide dismutase 3, extracellular; Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen | 0.975 |
| ATOX1 | UBC | ENSP00000316854 | ENSP00000344818 | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | ubiquitin C | 0.721 |
| ATP7A | ATOX1 | ENSP00000345728 | ENSP00000316854 | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | 0.999 |
| ATP7A | CCS | ENSP00000345728 | ENSP00000436318 | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | copper chaperone for superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) | 0.481 |
| ATP7A | COX11 | ENSP00000345728 | ENSP00000299335 | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.663 |
| ATP7A | COX17 | ENSP00000345728 | ENSP00000261070 | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | 0.753 |
| ATP7A | SLC31A1 | ENSP00000345728 | ENSP00000363329 | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | solute carrier family 31 (copper transporters), member 1; High-affinity, saturable copper transporter involved in dietary copper uptake | 0.855 |
| ATP7A | UBC | ENSP00000345728 | ENSP00000344818 | ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells | ubiquitin C | 0.703 |
| ATP7B | ATOX1 | ENSP00000242839 | ENSP00000316854 | ATPase, Cu++ transporting, beta polypeptide; Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile | ATX1 antioxidant protein 1 homolog (yeast); Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense | 0.999 |
| ATP7B | COX11 | ENSP00000242839 | ENSP00000299335 | ATPase, Cu++ transporting, beta polypeptide; Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.614 |
| ATP7B | COX17 | ENSP00000242839 | ENSP00000261070 | ATPase, Cu++ transporting, beta polypeptide; Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | 0.707 |
| ATP7B | SLC31A1 | ENSP00000242839 | ENSP00000363329 | ATPase, Cu++ transporting, beta polypeptide; Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile | solute carrier family 31 (copper transporters), member 1; High-affinity, saturable copper transporter involved in dietary copper uptake | 0.805 |
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