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STRINGSTRING
ARL9 ARL9 TMEM33 TMEM33 TAPT1 TAPT1 ANKRD50 ANKRD50 TRMT61A TRMT61A ADAD1 ADAD1 LIMCH1 LIMCH1 SPATA5 SPATA5 NPM1 NPM1 HUWE1 HUWE1 GABPA GABPA
"LIMCH1" - LIM and calponin homology domains 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
LIMCH1LIM and calponin homology domains 1 (1083 aa)    
Predicted Functional Partners:
HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (4374 aa)
        score_image       0.644
ARL9
ADP-ribosylation factor-like 9 (187 aa)
            score_image   0.632
TAPT1
transmembrane anterior posterior transformation 1; May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169 (567 aa)
            score_image   0.614
ANKRD50
ankyrin repeat domain 50 (1429 aa)
            score_image   0.609
TMEM33
transmembrane protein 33 (247 aa)
            score_image   0.605
ADAD1
adenosine deaminase domain containing 1 (testis-specific); Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity) (576 aa)
            score_image   0.595
SPATA5
spermatogenesis associated 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity) (893 aa)
            score_image   0.567
GABPA
GA binding protein transcription factor, alpha subunit 60kDa; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene (454 aa)
        score_image   score_image   0.548
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae); Catalytic subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (289 aa)
        score_image   score_image   0.543
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin) (294 aa)
        score_image   score_image   0.539
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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