SSR4 protein (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Score

SSR4

signal sequence receptor, delta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins (173 aa)

Predicted Functional Partners:

SSR3

0.998

SSR2

0.996

SEC61B

0.976

SSR1

0.918

SEC11A

0.856

SEC11C

0.832

TMED10

0.754

SEC61A1

0.719

DNAJC1

0.689

MAGT1

0.689

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJC1	MAGT1	ENSP00000366179	ENSP00000354649	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	0.576
DNAJC1	SEC61A1	ENSP00000366179	ENSP00000243253	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	Sec61 alpha 1 subunit (S. cerevisiae)	0.425
DNAJC1	SSR1	ENSP00000366179	ENSP00000244763	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	signal sequence receptor, alpha	0.523
DNAJC1	SSR2	ENSP00000366179	ENSP00000295702	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	signal sequence receptor, beta (translocon-associated protein beta); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins	0.525
DNAJC1	SSR3	ENSP00000366179	ENSP00000265044	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	signal sequence receptor, gamma (translocon-associated protein gamma); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins	0.538
DNAJC1	SSR4	ENSP00000366179	ENSP00000317331	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	signal sequence receptor, delta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins	0.689
MAGT1	DNAJC1	ENSP00000354649	ENSP00000366179	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	DnaJ (Hsp40) homolog, subfamily C, member 1; May modulate protein synthesis (By similarity)	0.576
MAGT1	SEC11A	ENSP00000354649	ENSP00000268220	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	0.758
MAGT1	SEC11C	ENSP00000354649	ENSP00000468633	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	SEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	0.761
MAGT1	SEC61A1	ENSP00000354649	ENSP00000243253	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	Sec61 alpha 1 subunit (S. cerevisiae)	0.952
MAGT1	SEC61B	ENSP00000354649	ENSP00000223641	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	Sec61 beta subunit; Necessary for protein translocation in the endoplasmic reticulum	0.866
MAGT1	SSR2	ENSP00000354649	ENSP00000295702	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	signal sequence receptor, beta (translocon-associated protein beta); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins	0.736
MAGT1	SSR3	ENSP00000354649	ENSP00000265044	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	signal sequence receptor, gamma (translocon-associated protein gamma); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins	0.644
MAGT1	SSR4	ENSP00000354649	ENSP00000317331	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	signal sequence receptor, delta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins	0.689
MAGT1	TMED10	ENSP00000354649	ENSP00000303145	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	transmembrane emp24-like trafficking protein 10 (yeast); Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act togther with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipi [...]	0.822
SEC11A	MAGT1	ENSP00000268220	ENSP00000354649	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	0.758
SEC11A	SEC11C	ENSP00000268220	ENSP00000468633	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	SEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	0.902
SEC11A	SEC61A1	ENSP00000268220	ENSP00000243253	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	Sec61 alpha 1 subunit (S. cerevisiae)	0.739
SEC11A	SEC61B	ENSP00000268220	ENSP00000223641	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	Sec61 beta subunit; Necessary for protein translocation in the endoplasmic reticulum	0.997
SEC11A	SSR1	ENSP00000268220	ENSP00000244763	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	signal sequence receptor, alpha	0.909

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