node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GPR125 | IGSF9B | ENSP00000334952 | ENSP00000317980 | G protein-coupled receptor 125; Orphan receptor | immunoglobulin superfamily, member 9B | 0.785 |
HSPG2 | IGSF9B | ENSP00000363827 | ENSP00000317980 | heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development | immunoglobulin superfamily, member 9B | 0.725 |
IGSF9B | GPR125 | ENSP00000317980 | ENSP00000334952 | immunoglobulin superfamily, member 9B | G protein-coupled receptor 125; Orphan receptor | 0.785 |
IGSF9B | HSPG2 | ENSP00000317980 | ENSP00000363827 | immunoglobulin superfamily, member 9B | heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development | 0.725 |
IGSF9B | LRRC3 | ENSP00000317980 | ENSP00000291592 | immunoglobulin superfamily, member 9B | leucine rich repeat containing 3 | 0.718 |
IGSF9B | LRRC3B | ENSP00000317980 | ENSP00000379880 | immunoglobulin superfamily, member 9B | leucine rich repeat containing 3B | 0.718 |
IGSF9B | LRRC3C | ENSP00000317980 | ENSP00000367157 | immunoglobulin superfamily, member 9B | leucine rich repeat containing 3C | 0.718 |
IGSF9B | MDGA1 | ENSP00000317980 | ENSP00000402584 | immunoglobulin superfamily, member 9B | MAM domain containing glycosylphosphatidylinositol anchor 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity) | 0.923 |
IGSF9B | NLGN2 | ENSP00000317980 | ENSP00000305288 | immunoglobulin superfamily, member 9B | neuroligin 2; Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma- aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of sign [...] | 0.859 |
IGSF9B | NYX | ENSP00000317980 | ENSP00000340328 | immunoglobulin superfamily, member 9B | nyctalopin | 0.718 |
IGSF9B | SLIT2 | ENSP00000317980 | ENSP00000422591 | immunoglobulin superfamily, member 9B | slit homolog 2 (Drosophila); Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once [...] | 0.718 |
IGSF9B | SLIT3 | ENSP00000317980 | ENSP00000430333 | immunoglobulin superfamily, member 9B | slit homolog 3 (Drosophila); May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors | 0.718 |
LRRC3 | IGSF9B | ENSP00000291592 | ENSP00000317980 | leucine rich repeat containing 3 | immunoglobulin superfamily, member 9B | 0.718 |
LRRC3B | IGSF9B | ENSP00000379880 | ENSP00000317980 | leucine rich repeat containing 3B | immunoglobulin superfamily, member 9B | 0.718 |
LRRC3C | IGSF9B | ENSP00000367157 | ENSP00000317980 | leucine rich repeat containing 3C | immunoglobulin superfamily, member 9B | 0.718 |
MDGA1 | IGSF9B | ENSP00000402584 | ENSP00000317980 | MAM domain containing glycosylphosphatidylinositol anchor 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity) | immunoglobulin superfamily, member 9B | 0.923 |
NLGN2 | IGSF9B | ENSP00000305288 | ENSP00000317980 | neuroligin 2; Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma- aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of sign [...] | immunoglobulin superfamily, member 9B | 0.859 |
NYX | IGSF9B | ENSP00000340328 | ENSP00000317980 | nyctalopin | immunoglobulin superfamily, member 9B | 0.718 |
SLIT2 | IGSF9B | ENSP00000422591 | ENSP00000317980 | slit homolog 2 (Drosophila); Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once [...] | immunoglobulin superfamily, member 9B | 0.718 |
SLIT2 | SLIT3 | ENSP00000422591 | ENSP00000430333 | slit homolog 2 (Drosophila); Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once [...] | slit homolog 3 (Drosophila); May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors | 0.901 |