| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FUT7 | FUT8 | ENSP00000318142 | ENSP00000353910 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | 0.763 |
| FUT7 | GATA3 | ENSP00000318142 | ENSP00000368632 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | GATA binding protein 3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5’-AGATAG-3’ | 0.899 |
| FUT7 | GCNT1 | ENSP00000318142 | ENSP00000365920 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | 0.761 |
| FUT7 | HECA | ENSP00000318142 | ENSP00000356630 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | headcase homolog (Drosophila); May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs | 0.770 |
| FUT7 | IL4 | ENSP00000318142 | ENSP00000231449 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | interleukin 4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes | 0.847 |
| FUT7 | SELE | ENSP00000318142 | ENSP00000331736 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | selectin E; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis | 0.860 |
| FUT7 | SELPLG | ENSP00000318142 | ENSP00000228463 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | selectin P ligand; A SLe(x)-type glycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. PSGL1 is critical for the initial leukocyte capture | 0.836 |
| FUT7 | ST3GAL6 | ENSP00000318142 | ENSP00000377717 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 | 0.942 |
| FUT7 | ST8SIA1 | ENSP00000318142 | ENSP00000379353 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid | 0.909 |
| FUT7 | ZBTB32 | ENSP00000318142 | ENSP00000262630 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | zinc finger and BTB domain containing 32; DNA-binding protein that binds to the to a 5’- TGTACAGTGT-3’ core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity) | 0.748 |
| FUT8 | FUT7 | ENSP00000353910 | ENSP00000318142 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | 0.763 |
| FUT8 | GCNT1 | ENSP00000353910 | ENSP00000365920 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | 0.433 |
| FUT8 | ST3GAL6 | ENSP00000353910 | ENSP00000377717 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 | 0.586 |
| GATA3 | FUT7 | ENSP00000368632 | ENSP00000318142 | GATA binding protein 3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5’-AGATAG-3’ | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | 0.899 |
| GATA3 | IL4 | ENSP00000368632 | ENSP00000231449 | GATA binding protein 3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5’-AGATAG-3’ | interleukin 4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes | 0.993 |
| GATA3 | ZBTB32 | ENSP00000368632 | ENSP00000262630 | GATA binding protein 3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5’-AGATAG-3’ | zinc finger and BTB domain containing 32; DNA-binding protein that binds to the to a 5’- TGTACAGTGT-3’ core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity) | 0.952 |
| GCNT1 | FUT7 | ENSP00000365920 | ENSP00000318142 | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | 0.761 |
| GCNT1 | FUT8 | ENSP00000365920 | ENSP00000353910 | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | 0.433 |
| GCNT1 | HECA | ENSP00000365920 | ENSP00000356630 | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | headcase homolog (Drosophila); May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs | 0.472 |
| HECA | FUT7 | ENSP00000356630 | ENSP00000318142 | headcase homolog (Drosophila); May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs | fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens | 0.770 |
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