Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | MRPS24 | mitochondrial ribosomal protein S24 (167 aa) | ||||||||||||
Predicted Functional Partners:
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 | MRPS15 | mitochondrial ribosomal protein S15 (257 aa) |
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0.833 | |||||||||
 | MRPS12 | mitochondrial ribosomal protein S12 (138 aa) |
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0.774 | ||||||||
 | MRPS9 | mitochondrial ribosomal protein S9 (396 aa) |
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0.771 | |||||||||
 | MRPS16 | mitochondrial ribosomal protein S16 (137 aa) |
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0.771 | ||||||||
 | MRPS10 | mitochondrial ribosomal protein S10 (201 aa) |
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0.763 | ||||||||
 | MRPS2 | mitochondrial ribosomal protein S2 (296 aa) |
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0.759 | ||||||||
 | MRPL18 | mitochondrial ribosomal protein L18; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA (180 aa) |
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0.745 | |||||||||
 | MRPS18A | mitochondrial ribosomal protein S18A (196 aa) |
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0.737 | ||||||||
 | MRPS14 | mitochondrial ribosomal protein S14 (128 aa) |
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0.726 | ||||||||
 | MRPS5 | mitochondrial ribosomal protein S5 (430 aa) |
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0.704 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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