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STRINGSTRING
CARK CARK SAP30BP SAP30BP SLC35B4 SLC35B4 UBR3 UBR3 SUPT5H SUPT5H CSRNP3 CSRNP3 TNNI3K TNNI3K ASXL1 ASXL1 ZBTB39 ZBTB39 GPR84 GPR84 SMCR7L SMCR7L
"CSRNP3" - cysteine-serine-rich nuclear protein 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CSRNP3cysteine-serine-rich nuclear protein 3; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity. Plays a role in apoptosis (By similarity) (585 aa)    
Predicted Functional Partners:
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae); Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promot [...] (1087 aa)
            score_image   0.575
SAP30BP
SAP30 binding protein; Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes (308 aa)
            score_image   0.573
SLC35B4
solute carrier family 35, member B4; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi (331 aa)
            score_image   0.565
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission (463 aa)
            score_image   0.483
ZBTB39
zinc finger and BTB domain containing 39; May be involved in transcriptional regulation (712 aa)
            score_image   0.483
ASXL1
additional sex combs like 1 (Drosophila) (1541 aa)
            score_image   0.463
GPR84
G protein-coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10-0), undecanoic acid (C11-0) and lauric acid (C12-0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (396 aa)
            score_image   0.451
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative); E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity) (1888 aa)
            score_image   0.447
CARK
FPGT-TNNI3K readthrough; May play a role in cardiac physiology (936 aa)
            score_image   0.441
TNNI3K
TNNI3 interacting kinase; May play a role in cardiac physiology (936 aa)
            score_image   0.419
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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