ELMOD3 protein (Homo sapiens) - STRING network view

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Score

ELMOD3

ELMO/CED-12 domain containing 3 (391 aa)

Predicted Functional Partners:

ELMOD2

0.774

ELMOD1

0.771

ELMO3

0.712

ELMO2

0.629

ELMO1

0.606

ARFGAP1

0.493

C6orf118

0.483

UBAC2

0.432

ARL13B

0.429

ARL2

0.413

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARFGAP1	ARL13B	ENSP00000314615	ENSP00000377769	ADP-ribosylation factor GTPase activating protein 1	ADP-ribosylation factor-like 13B	0.414
ARFGAP1	ELMO3	ENSP00000314615	ENSP00000377566	ADP-ribosylation factor GTPase activating protein 1	engulfment and cell motility 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity)	0.450
ARFGAP1	ELMOD1	ENSP00000314615	ENSP00000265840	ADP-ribosylation factor GTPase activating protein 1	ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family	0.574
ARFGAP1	ELMOD2	ENSP00000314615	ENSP00000326342	ADP-ribosylation factor GTPase activating protein 1	ELMO/CED-12 domain containing 2; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses	0.618
ARFGAP1	ELMOD3	ENSP00000314615	ENSP00000318264	ADP-ribosylation factor GTPase activating protein 1	ELMO/CED-12 domain containing 3	0.493
ARL13B	ARFGAP1	ENSP00000377769	ENSP00000314615	ADP-ribosylation factor-like 13B	ADP-ribosylation factor GTPase activating protein 1	0.414
ARL13B	ELMOD1	ENSP00000377769	ENSP00000265840	ADP-ribosylation factor-like 13B	ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family	0.429
ARL13B	ELMOD2	ENSP00000377769	ENSP00000326342	ADP-ribosylation factor-like 13B	ELMO/CED-12 domain containing 2; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses	0.429
ARL13B	ELMOD3	ENSP00000377769	ENSP00000318264	ADP-ribosylation factor-like 13B	ELMO/CED-12 domain containing 3	0.429
ARL2	ELMOD1	ENSP00000246747	ENSP00000265840	ADP-ribosylation factor-like 2; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of T [...]	ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family	0.418
ARL2	ELMOD2	ENSP00000246747	ENSP00000326342	ADP-ribosylation factor-like 2; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of T [...]	ELMO/CED-12 domain containing 2; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses	0.556
ARL2	ELMOD3	ENSP00000246747	ENSP00000318264	ADP-ribosylation factor-like 2; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of T [...]	ELMO/CED-12 domain containing 3	0.413
C6orf118	ELMOD3	ENSP00000230301	ENSP00000318264	chromosome 6 open reading frame 118	ELMO/CED-12 domain containing 3	0.483
C6orf118	UBAC2	ENSP00000230301	ENSP00000383911	chromosome 6 open reading frame 118	UBA domain containing 2	0.497
ELMO1	ELMO2	ENSP00000312185	ENSP00000290246	engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1	engulfment and cell motility 2	0.900
ELMO1	ELMOD1	ENSP00000312185	ENSP00000265840	engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1	ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family	0.613
ELMO1	ELMOD2	ENSP00000312185	ENSP00000326342	engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1	ELMO/CED-12 domain containing 2; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses	0.612
ELMO1	ELMOD3	ENSP00000312185	ENSP00000318264	engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1	ELMO/CED-12 domain containing 3	0.606
ELMO2	ELMO1	ENSP00000290246	ENSP00000312185	engulfment and cell motility 2	engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1	0.900
ELMO2	ELMOD1	ENSP00000290246	ENSP00000265840	engulfment and cell motility 2	ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family	0.612

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