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STRINGSTRING
CYP27A1 CYP27A1 HSF4 HSF4 VSIG2 VSIG2 IGSF3 IGSF3 LRRC20 LRRC20 TAPBPL TAPBPL
"VSIG2" - V-set and immunoglobulin domain containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VSIG2V-set and immunoglobulin domain containing 2 (327 aa)    
Predicted Functional Partners:
TAPBPL
TAP binding protein-like (468 aa)
        score_image       0.841
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1; Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta- cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3- 25-hydroxylase activity (531 aa)
            score_image   0.811
HSF4
heat shock transcription factor 4; DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription (492 aa)
            score_image   0.756
IGSF3
immunoglobulin superfamily, member 3 (1214 aa)
        score_image   score_image   0.571
LRRC20
leucine rich repeat containing 20 (184 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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