AQP11 protein (Homo sapiens) - STRING network view

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AQP11

aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) (271 aa)

Predicted Functional Partners:

AQP6

0.818

AQP7

0.791

AQP8

0.768

AQP10

0.762

AQP1

0.756

MIP

0.743

AQP5

0.714

ENSG00000250424

0.713

AQP4

0.675

AQP3

0.671

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQP1	AQP11	ENSP00000311165	ENSP00000318770	aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	0.756
AQP1	AQP7	ENSP00000311165	ENSP00000297988	aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient	aquaporin 7; Forms a channel for water and glycerol	0.401
AQP10	AQP11	ENSP00000318355	ENSP00000318770	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	0.762
AQP10	AQP4	ENSP00000318355	ENSP00000372654	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system	0.408
AQP10	AQP5	ENSP00000318355	ENSP00000293599	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions	0.876
AQP10	AQP6	ENSP00000318355	ENSP00000320247	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	aquaporin 6, kidney specific; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism (By similarity)	0.927
AQP10	AQP8	ENSP00000318355	ENSP00000219660	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	aquaporin 8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea	0.917
AQP10	MIP	ENSP00000318355	ENSP00000257979	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	major intrinsic protein of lens fiber; Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity)	0.908
AQP11	AQP1	ENSP00000318770	ENSP00000311165	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient	0.756
AQP11	AQP10	ENSP00000318770	ENSP00000318355	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol	0.762
AQP11	AQP3	ENSP00000318770	ENSP00000297991	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...]	0.671
AQP11	AQP4	ENSP00000318770	ENSP00000372654	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system	0.675
AQP11	AQP5	ENSP00000318770	ENSP00000293599	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions	0.714
AQP11	AQP6	ENSP00000318770	ENSP00000320247	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 6, kidney specific; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism (By similarity)	0.818
AQP11	AQP7	ENSP00000318770	ENSP00000297988	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 7; Forms a channel for water and glycerol	0.791
AQP11	AQP8	ENSP00000318770	ENSP00000219660	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	aquaporin 8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea	0.768
AQP11	ENSG00000250424	ENSP00000318770	ENSP00000421315	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	Uncharacterized protein	0.713
AQP11	MIP	ENSP00000318770	ENSP00000257979	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	major intrinsic protein of lens fiber; Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity)	0.743
AQP3	AQP11	ENSP00000297991	ENSP00000318770	aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...]	aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)	0.671
AQP3	AQP4	ENSP00000297991	ENSP00000372654	aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...]	aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system	0.412

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