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ZNF276 ZNF276 RAB30 RAB30 TGOLN2 TGOLN2 GOLGA1 GOLGA1 GOLGA4 GOLGA4 MTHFD2 MTHFD2 GCC1 GCC1 GRIP1 GRIP1 GTF2I GTF2I CEP57 CEP57 COIL COIL
"GCC1" - GRIP and coiled-coil domain containing 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
GCC1GRIP and coiled-coil domain containing 1; Probably involved in maintaining Golgi structure (775 aa)    
Predicted Functional Partners:
RAB30
RAB30, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins (203 aa)
            score_image   0.846
GOLGA4
golgin A4; May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1 (2243 aa)
            score_image   0.794
GRIP1
glutamate receptor interacting protein 1; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (1076 aa)
            score_image   0.761
CEP57
centrosomal protein 57kDa; Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring- like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1 (500 aa)
        score_image       0.712
GTF2I
general transcription factor IIi (998 aa)
        score_image       0.692
COIL
coilin; Is a component of the nuclear coiled bodies (CBS) which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. During mitosis, CBS disassemble, coinciding with a mitotic-specific phosphorylation of p80 coilin (576 aa)
        score_image   score_image   0.671
TGOLN2
trans-golgi network protein 2 (453 aa)
            score_image   0.653
GOLGA1
golgin A1; Probably involved in maintaining Golgi structure (767 aa)
            score_image   0.646
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (350 aa)
        score_image       0.644
ZNF276
zinc finger protein 276; May be involved in transcriptional regulation (614 aa)
        score_image       0.638
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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