node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCL2L13 | GABARAPL2 | ENSP00000318883 | ENSP00000037243 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | GABA(A) receptor-associated protein-like 2; Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy (By similarity) | 0.632 |
BCL2L13 | HSPD1 | ENSP00000318883 | ENSP00000340019 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | heat shock 60kDa protein 1 (chaperonin); Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix | 0.576 |
BCL2L13 | NINJ2 | ENSP00000318883 | ENSP00000307552 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | ninjurin 2; Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues | 0.508 |
BCL2L13 | PLLP | ENSP00000318883 | ENSP00000219207 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity) | 0.508 |
BCL2L13 | SLC25A4 | ENSP00000318883 | ENSP00000281456 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane | 0.576 |
BCL2L13 | TMEM128 | ENSP00000318883 | ENSP00000254742 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | transmembrane protein 128 | 0.581 |
BCL2L13 | TMEM86B | ENSP00000318883 | ENSP00000321038 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | transmembrane protein 86B; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties | 0.581 |
BCL2L13 | TMUB2 | ENSP00000318883 | ENSP00000444565 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | transmembrane and ubiquitin-like domain containing 2 | 0.543 |
BCL2L13 | UBC | ENSP00000318883 | ENSP00000344818 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | ubiquitin C | 0.620 |
BCL2L13 | UPK1B | ENSP00000318883 | ENSP00000264234 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | uroplakin 1B; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity) | 0.543 |
GABARAPL2 | BCL2L13 | ENSP00000037243 | ENSP00000318883 | GABA(A) receptor-associated protein-like 2; Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy (By similarity) | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.632 |
GABARAPL2 | UBC | ENSP00000037243 | ENSP00000344818 | GABA(A) receptor-associated protein-like 2; Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy (By similarity) | ubiquitin C | 0.782 |
HSPD1 | BCL2L13 | ENSP00000340019 | ENSP00000318883 | heat shock 60kDa protein 1 (chaperonin); Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.576 |
HSPD1 | UBC | ENSP00000340019 | ENSP00000344818 | heat shock 60kDa protein 1 (chaperonin); Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix | ubiquitin C | 0.998 |
NINJ2 | BCL2L13 | ENSP00000307552 | ENSP00000318883 | ninjurin 2; Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.508 |
PLLP | BCL2L13 | ENSP00000219207 | ENSP00000318883 | plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity) | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.508 |
SLC25A4 | BCL2L13 | ENSP00000281456 | ENSP00000318883 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.576 |
SLC25A4 | UBC | ENSP00000281456 | ENSP00000344818 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane | ubiquitin C | 0.972 |
TMEM128 | BCL2L13 | ENSP00000254742 | ENSP00000318883 | transmembrane protein 128 | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.581 |
TMEM86B | BCL2L13 | ENSP00000321038 | ENSP00000318883 | transmembrane protein 86B; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties | BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis | 0.581 |