FAM133A protein (Homo sapiens) - STRING network view

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FAM133A

family with sequence similarity 133, member A (248 aa)

Predicted Functional Partners:

FAM9C

0.537

PTPN20A

0.499

NOS1AP

0.489

CCDC62

0.457

ANKRD45

0.456

ZNF645

0.416

MAP7D3

0.414

ARHGAP36

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD45	FAM133A	ENSP00000331268	ENSP00000318974	ankyrin repeat domain 45	family with sequence similarity 133, member A	0.456
ANKRD45	PTPN20A	ENSP00000331268	ENSP00000363459	ankyrin repeat domain 45	protein tyrosine phosphatase, non-receptor type 20A	0.562
ARHGAP36	FAM133A	ENSP00000276211	ENSP00000318974	Rho GTPase activating protein 36; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	family with sequence similarity 133, member A	0.404
ARHGAP36	ZNF645	ENSP00000276211	ENSP00000323348	Rho GTPase activating protein 36; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	zinc finger protein 645; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates	0.471
CCDC62	FAM133A	ENSP00000253079	ENSP00000318974	coiled-coil domain containing 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR	family with sequence similarity 133, member A	0.457
FAM133A	ANKRD45	ENSP00000318974	ENSP00000331268	family with sequence similarity 133, member A	ankyrin repeat domain 45	0.456
FAM133A	ARHGAP36	ENSP00000318974	ENSP00000276211	family with sequence similarity 133, member A	Rho GTPase activating protein 36; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	0.404
FAM133A	CCDC62	ENSP00000318974	ENSP00000253079	family with sequence similarity 133, member A	coiled-coil domain containing 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR	0.457
FAM133A	FAM9C	ENSP00000318974	ENSP00000334430	family with sequence similarity 133, member A	family with sequence similarity 9, member C	0.537
FAM133A	MAP7D3	ENSP00000318974	ENSP00000318086	family with sequence similarity 133, member A	MAP7 domain containing 3	0.414
FAM133A	NOS1AP	ENSP00000318974	ENSP00000355133	family with sequence similarity 133, member A	nitric oxide synthase 1 (neuronal) adaptor protein; Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity)	0.489
FAM133A	PTPN20A	ENSP00000318974	ENSP00000363459	family with sequence similarity 133, member A	protein tyrosine phosphatase, non-receptor type 20A	0.499
FAM133A	ZNF645	ENSP00000318974	ENSP00000323348	family with sequence similarity 133, member A	zinc finger protein 645; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates	0.416
FAM9C	FAM133A	ENSP00000334430	ENSP00000318974	family with sequence similarity 9, member C	family with sequence similarity 133, member A	0.537
MAP7D3	FAM133A	ENSP00000318086	ENSP00000318974	MAP7 domain containing 3	family with sequence similarity 133, member A	0.414
NOS1AP	FAM133A	ENSP00000355133	ENSP00000318974	nitric oxide synthase 1 (neuronal) adaptor protein; Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity)	family with sequence similarity 133, member A	0.489
PTPN20A	ANKRD45	ENSP00000363459	ENSP00000331268	protein tyrosine phosphatase, non-receptor type 20A	ankyrin repeat domain 45	0.562
PTPN20A	FAM133A	ENSP00000363459	ENSP00000318974	protein tyrosine phosphatase, non-receptor type 20A	family with sequence similarity 133, member A	0.499
ZNF645	ARHGAP36	ENSP00000323348	ENSP00000276211	zinc finger protein 645; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates	Rho GTPase activating protein 36; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	0.471
ZNF645	FAM133A	ENSP00000323348	ENSP00000318974	zinc finger protein 645; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates	family with sequence similarity 133, member A	0.416

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