STK17A protein (Homo sapiens) - STRING network view

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STK17A

serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species (414 aa)

Predicted Functional Partners:

UBC

0.752

MYL9

0.729

MYL12B

0.729

MYL12A

0.729

MCHR2

0.593

CHP1

0.567

COL21A1

0.538

DAP

0.531

GPR45

0.485

GPR63

0.485

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHP1	STK17A	ENSP00000335632	ENSP00000319192	calcineurin-like EF hand protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...]	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.567
CHP1	UBC	ENSP00000335632	ENSP00000344818	calcineurin-like EF hand protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...]	ubiquitin C	0.650
COL21A1	STK17A	ENSP00000244728	ENSP00000319192	collagen, type XXI, alpha 1	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.538
DAP	STK17A	ENSP00000230895	ENSP00000319192	death-associated protein; Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.531
DAP	UBC	ENSP00000230895	ENSP00000344818	death-associated protein; Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death	ubiquitin C	0.500
GPR45	STK17A	ENSP00000258456	ENSP00000319192	G protein-coupled receptor 45; Orphan receptor. May play a role in brain function	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.485
GPR63	STK17A	ENSP00000229955	ENSP00000319192	G protein-coupled receptor 63; Orphan receptor. May play a role in brain function	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.485
MCHR2	STK17A	ENSP00000281806	ENSP00000319192	melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.593
MYL12A	MYL9	ENSP00000217652	ENSP00000279022	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	0.692
MYL12A	STK17A	ENSP00000217652	ENSP00000319192	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.729
MYL12A	UBC	ENSP00000217652	ENSP00000344818	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	ubiquitin C	0.948
MYL12B	MYL9	ENSP00000237500	ENSP00000279022	myosin, light chain 12B, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	0.900
MYL12B	STK17A	ENSP00000237500	ENSP00000319192	myosin, light chain 12B, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.729
MYL12B	UBC	ENSP00000237500	ENSP00000344818	myosin, light chain 12B, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	ubiquitin C	0.947
MYL9	MYL12A	ENSP00000279022	ENSP00000217652	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	0.692
MYL9	MYL12B	ENSP00000279022	ENSP00000237500	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	myosin, light chain 12B, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	0.900
MYL9	STK17A	ENSP00000279022	ENSP00000319192	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	0.729
MYL9	UBC	ENSP00000279022	ENSP00000344818	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	ubiquitin C	0.861
STK17A	CHP1	ENSP00000319192	ENSP00000335632	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	calcineurin-like EF hand protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...]	0.567
STK17A	COL21A1	ENSP00000319192	ENSP00000244728	serine/threonine kinase 17a; Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species	collagen, type XXI, alpha 1	0.538

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