BASP1 protein (Homo sapiens) - STRING network view

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BASP1

brain abundant, membrane attached signal protein 1 (227 aa)

Predicted Functional Partners:

ATP5A1

0.904

WT1

0.817

UBC

0.812

MARCKS

0.758

GAP43

0.681

HSPA5

0.652

EFTUD2

0.644

TRNT1

0.509

UBXN1

0.468

INSR

0.457

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5A1	BASP1	ENSP00000282050	ENSP00000319281	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of [...]	brain abundant, membrane attached signal protein 1	0.904
ATP5A1	EFTUD2	ENSP00000282050	ENSP00000392094	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of [...]	elongation factor Tu GTP binding domain containing 2; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP	0.761
ATP5A1	HSPA5	ENSP00000282050	ENSP00000324173	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of [...]	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER	0.747
ATP5A1	UBC	ENSP00000282050	ENSP00000344818	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of [...]	ubiquitin C	0.997
BASP1	ATP5A1	ENSP00000319281	ENSP00000282050	brain abundant, membrane attached signal protein 1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of [...]	0.904
BASP1	EFTUD2	ENSP00000319281	ENSP00000392094	brain abundant, membrane attached signal protein 1	elongation factor Tu GTP binding domain containing 2; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP	0.644
BASP1	GAP43	ENSP00000319281	ENSP00000377372	brain abundant, membrane attached signal protein 1	growth associated protein 43; This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction	0.681
BASP1	HSPA5	ENSP00000319281	ENSP00000324173	brain abundant, membrane attached signal protein 1	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER	0.652
BASP1	INSR	ENSP00000319281	ENSP00000303830	brain abundant, membrane attached signal protein 1	insulin receptor; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src- homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosines residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lead to the act [...]	0.457
BASP1	MARCKS	ENSP00000319281	ENSP00000357624	brain abundant, membrane attached signal protein 1	myristoylated alanine-rich protein kinase C substrate; MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein	0.758
BASP1	TRNT1	ENSP00000319281	ENSP00000251607	brain abundant, membrane attached signal protein 1	tRNA nucleotidyl transferase, CCA-adding, 1; Isoform 1- Adds and repairs the conserved 3’-CCA sequence necessary for the attachment of amino acids to the 3’ terminus of tRNA molecules, using CTP and ATP as substrates	0.509
BASP1	UBC	ENSP00000319281	ENSP00000344818	brain abundant, membrane attached signal protein 1	ubiquitin C	0.812
BASP1	UBXN1	ENSP00000319281	ENSP00000294119	brain abundant, membrane attached signal protein 1	UBX domain protein 1; Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds ’Lys-6’-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol	0.468
BASP1	WT1	ENSP00000319281	ENSP00000331327	brain abundant, membrane attached signal protein 1	Wilms tumor 1	0.817
EFTUD2	ATP5A1	ENSP00000392094	ENSP00000282050	elongation factor Tu GTP binding domain containing 2; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of [...]	0.761
EFTUD2	BASP1	ENSP00000392094	ENSP00000319281	elongation factor Tu GTP binding domain containing 2; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP	brain abundant, membrane attached signal protein 1	0.644
EFTUD2	HSPA5	ENSP00000392094	ENSP00000324173	elongation factor Tu GTP binding domain containing 2; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER	0.541
EFTUD2	UBC	ENSP00000392094	ENSP00000344818	elongation factor Tu GTP binding domain containing 2; Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP	ubiquitin C	0.976
GAP43	BASP1	ENSP00000377372	ENSP00000319281	growth associated protein 43; This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction	brain abundant, membrane attached signal protein 1	0.681
GAP43	MARCKS	ENSP00000377372	ENSP00000357624	growth associated protein 43; This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction	myristoylated alanine-rich protein kinase C substrate; MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein	0.472

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