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STRINGSTRING
ENSG00000255439 ENSG00000255439 GGCX GGCX MT1X MT1X NQO1 NQO1 ODC1 ODC1 UBC UBC MT1G MT1G APRT APRT TP53 TP53 ADK ADK MT1H MT1H
"NQO1" - NAD(P)H dehydrogenase, quinone 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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Predicted Interactions
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protein homology
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NQO1NAD(P)H dehydrogenase, quinone 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis (274 aa)    
Predicted Functional Partners:
ODC1
ornithine decarboxylase 1 (461 aa)
        score_image score_image score_image   0.921
ENSG00000255439
Uncharacterized protein (166 aa)
          score_image     0.900
GGCX
gamma-glutamyl carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide (758 aa)
          score_image     0.900
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity) (393 aa)
        score_image   score_image   0.845
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.837
APRT
adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (180 aa)
            score_image   0.752
ADK
adenosine kinase; ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides (362 aa)
            score_image   0.741
MT1X
metallothionein 1X; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids (61 aa)
            score_image   0.687
MT1H
metallothionein 1H; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids (By similarity) (61 aa)
            score_image   0.686
MT1G
metallothionein 1G; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids (61 aa)
            score_image   0.683
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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