ITFG1 protein (Homo sapiens) - STRING network view

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Score

ITFG1

integrin alpha FG-GAP repeat containing 1; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity) (612 aa)

Predicted Functional Partners:

TIPIN

0.750

LONP2

0.620

CRELD2

0.529

N4BP1

0.521

ABCC12

0.491

UBC

0.483

DUSP11

0.464

CLPTM1

0.456

DNAJA2

0.456

GPT2

0.418

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC12	DUSP11	ENSP00000311030	ENSP00000272444	ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity)	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Possesses RNA 5’-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism	0.433
ABCC12	ITFG1	ENSP00000311030	ENSP00000319918	ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity)	integrin alpha FG-GAP repeat containing 1; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)	0.491
ABCC12	LONP2	ENSP00000311030	ENSP00000285737	ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity)	lon peptidase 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1	0.540
ABCC12	N4BP1	ENSP00000311030	ENSP00000262384	ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity)	NEDD4 binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH’s substrates and impairing ubiquitination of substrates (By similarity)	0.448
ABCC12	UBC	ENSP00000311030	ENSP00000344818	ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity)	ubiquitin C	0.648
CLPTM1	CRELD2	ENSP00000336994	ENSP00000383938	cleft lip and palate associated transmembrane protein 1; May play a role in T-cell development (By similarity)	cysteine-rich with EGF-like domains 2	0.474
CLPTM1	ITFG1	ENSP00000336994	ENSP00000319918	cleft lip and palate associated transmembrane protein 1; May play a role in T-cell development (By similarity)	integrin alpha FG-GAP repeat containing 1; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)	0.456
CLPTM1	UBC	ENSP00000336994	ENSP00000344818	cleft lip and palate associated transmembrane protein 1; May play a role in T-cell development (By similarity)	ubiquitin C	0.849
CRELD2	CLPTM1	ENSP00000383938	ENSP00000336994	cysteine-rich with EGF-like domains 2	cleft lip and palate associated transmembrane protein 1; May play a role in T-cell development (By similarity)	0.474
CRELD2	ITFG1	ENSP00000383938	ENSP00000319918	cysteine-rich with EGF-like domains 2	integrin alpha FG-GAP repeat containing 1; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)	0.529
DNAJA2	GPT2	ENSP00000314030	ENSP00000345282	DnaJ (Hsp40) homolog, subfamily A, member 2; Co-chaperone of Hsc70	glutamic pyruvate transaminase (alanine aminotransferase) 2; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate	0.469
DNAJA2	ITFG1	ENSP00000314030	ENSP00000319918	DnaJ (Hsp40) homolog, subfamily A, member 2; Co-chaperone of Hsc70	integrin alpha FG-GAP repeat containing 1; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)	0.456
DNAJA2	LONP2	ENSP00000314030	ENSP00000285737	DnaJ (Hsp40) homolog, subfamily A, member 2; Co-chaperone of Hsc70	lon peptidase 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1	0.655
DNAJA2	N4BP1	ENSP00000314030	ENSP00000262384	DnaJ (Hsp40) homolog, subfamily A, member 2; Co-chaperone of Hsc70	NEDD4 binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH’s substrates and impairing ubiquitination of substrates (By similarity)	0.442
DNAJA2	UBC	ENSP00000314030	ENSP00000344818	DnaJ (Hsp40) homolog, subfamily A, member 2; Co-chaperone of Hsc70	ubiquitin C	0.994
DUSP11	ABCC12	ENSP00000272444	ENSP00000311030	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Possesses RNA 5’-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism	ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity)	0.433
DUSP11	ITFG1	ENSP00000272444	ENSP00000319918	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Possesses RNA 5’-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism	integrin alpha FG-GAP repeat containing 1; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)	0.464
DUSP11	LONP2	ENSP00000272444	ENSP00000285737	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Possesses RNA 5’-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism	lon peptidase 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1	0.526
DUSP11	N4BP1	ENSP00000272444	ENSP00000262384	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Possesses RNA 5’-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism	NEDD4 binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH’s substrates and impairing ubiquitination of substrates (By similarity)	0.450
DUSP11	UBC	ENSP00000272444	ENSP00000344818	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Possesses RNA 5’-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism	ubiquitin C	0.507

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