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STRINGSTRING
PHYH PHYH TFAP4 TFAP4 RAD54L2 RAD54L2 PHYHIP PHYHIP DYRK1A DYRK1A SGK196 SGK196 BAI1 BAI1
"PHYHIP" - phytanoyl-CoA 2-hydroxylase interacting protein in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
PHYHIPphytanoyl-CoA 2-hydroxylase interacting protein; Its interaction with PHYH suggests a role in the development of the central system (330 aa)    
Predicted Functional Partners:
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 (763 aa)
        score_image   score_image   0.945
PHYH
phytanoyl-CoA 2-hydroxylase; Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA (338 aa)
        score_image   score_image   0.940
BAI1
brain-specific angiogenesis inhibitor 1; Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain (1584 aa)
        score_image   score_image   0.760
RAD54L2
RAD54-like 2 (S. cerevisiae); DNA helicase that modulates androgen receptor (AR)- dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro (By similarity) (1467 aa)
            score_image   0.533
SGK196
Protein kinase-like protein SgK196 (350 aa)
            score_image   0.506
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4); Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5’- CAGCTG-3’ (338 aa)
            score_image   0.471
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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