GDPD4 protein (Homo sapiens) - STRING network view

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GDPD4

glycerophosphodiester phosphodiesterase domain containing 4 (520 aa)

Predicted Functional Partners:

GPCPD1

0.581

FAM228A

0.568

PRAF2

0.565

PDZD4

0.534

TSPO2

0.530

TSPO

0.530

H2AFY

0.518

H2AFY2

0.518

GPD2

0.516

GK5

0.505

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM228A	GDPD4	ENSP00000295150	ENSP00000320815	family with sequence similarity 228, member A	glycerophosphodiester phosphodiesterase domain containing 4	0.568
FAM228A	PDZD4	ENSP00000295150	ENSP00000164640	family with sequence similarity 228, member A	PDZ domain containing 4	0.539
GDPD4	FAM228A	ENSP00000320815	ENSP00000295150	glycerophosphodiester phosphodiesterase domain containing 4	family with sequence similarity 228, member A	0.568
GDPD4	GK5	ENSP00000320815	ENSP00000418001	glycerophosphodiester phosphodiesterase domain containing 4	glycerol kinase 5 (putative)	0.505
GDPD4	GPCPD1	ENSP00000320815	ENSP00000368305	glycerophosphodiester phosphodiesterase domain containing 4	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae); May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity (By similarity)	0.581
GDPD4	GPD2	ENSP00000320815	ENSP00000308610	glycerophosphodiester phosphodiesterase domain containing 4	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.516
GDPD4	H2AFY	ENSP00000320815	ENSP00000423563	glycerophosphodiester phosphodiesterase domain containing 4	H2A histone family, member Y; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Involved in stable X chromosome inactiv [...]	0.518
GDPD4	H2AFY2	ENSP00000320815	ENSP00000362352	glycerophosphodiester phosphodiesterase domain containing 4	H2A histone family, member Y2; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome [...]	0.518
GDPD4	PDZD4	ENSP00000320815	ENSP00000164640	glycerophosphodiester phosphodiesterase domain containing 4	PDZ domain containing 4	0.534
GDPD4	PRAF2	ENSP00000320815	ENSP00000365570	glycerophosphodiester phosphodiesterase domain containing 4	PRA1 domain family, member 2; May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis	0.565
GDPD4	TSPO	ENSP00000320815	ENSP00000328973	glycerophosphodiester phosphodiesterase domain containing 4	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.530
GDPD4	TSPO2	ENSP00000320815	ENSP00000362255	glycerophosphodiester phosphodiesterase domain containing 4	translocator protein 2; Binds cholesterol and mediates its redistribution during erythropoiesis which may play a role in erythrocyte maturation	0.530
GK5	GDPD4	ENSP00000418001	ENSP00000320815	glycerol kinase 5 (putative)	glycerophosphodiester phosphodiesterase domain containing 4	0.505
GK5	GPCPD1	ENSP00000418001	ENSP00000368305	glycerol kinase 5 (putative)	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae); May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity (By similarity)	0.505
GK5	GPD2	ENSP00000418001	ENSP00000308610	glycerol kinase 5 (putative)	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.884
GPCPD1	GDPD4	ENSP00000368305	ENSP00000320815	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae); May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity (By similarity)	glycerophosphodiester phosphodiesterase domain containing 4	0.581
GPCPD1	GK5	ENSP00000368305	ENSP00000418001	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae); May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity (By similarity)	glycerol kinase 5 (putative)	0.505
GPCPD1	GPD2	ENSP00000368305	ENSP00000308610	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae); May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity (By similarity)	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.516
GPD2	GDPD4	ENSP00000308610	ENSP00000320815	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	glycerophosphodiester phosphodiesterase domain containing 4	0.516
GPD2	GK5	ENSP00000308610	ENSP00000418001	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	glycerol kinase 5 (putative)	0.884

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