Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
CILP2 CILP2 ANGPTL3 ANGPTL3 TRIB1 TRIB1 GALNT2 GALNT2 SORT1 SORT1 MMAB MMAB PBX4 PBX4 MLXIPL MLXIPL SCD5 SCD5 NIF3L1 NIF3L1 MLX MLX
"MLXIPL" - MLX interacting protein-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLXIPLMLX interacting protein-like (852 aa)    
Predicted Functional Partners:
MLX
MLX, MAX dimerization protein (298 aa)
        score_image   score_image score_image 0.832
SCD5
stearoyl-CoA desaturase 5; Fatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position (330 aa)
            score_image   0.728
CILP2
cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) (1156 aa)
            score_image   0.660
PBX4
pre-B-cell leukemia homeobox 4 (374 aa)
            score_image   0.635
GALNT2
UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region (571 aa)
            score_image   0.584
TRIB1
tribbles homolog 1 (Drosophila); Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity (372 aa)
            score_image   0.584
ANGPTL3
angiopoietin-like 3 (460 aa)
            score_image   0.581
SORT1
sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] (831 aa)
            score_image   0.580
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) (377 aa)
        score_image       0.576
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type (250 aa)
            score_image   0.568
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (42%)