node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANGPTL3 | CILP2 | ENSP00000360170 | ENSP00000291495 | angiopoietin-like 3 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | 0.564 |
ANGPTL3 | GALNT2 | ENSP00000360170 | ENSP00000355632 | angiopoietin-like 3 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | 0.897 |
ANGPTL3 | MLXIPL | ENSP00000360170 | ENSP00000320886 | angiopoietin-like 3 | MLX interacting protein-like | 0.581 |
ANGPTL3 | MMAB | ENSP00000360170 | ENSP00000445920 | angiopoietin-like 3 | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.418 |
ANGPTL3 | PBX4 | ENSP00000360170 | ENSP00000251203 | angiopoietin-like 3 | pre-B-cell leukemia homeobox 4 | 0.471 |
ANGPTL3 | SORT1 | ENSP00000360170 | ENSP00000256637 | angiopoietin-like 3 | sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] | 0.472 |
ANGPTL3 | TRIB1 | ENSP00000360170 | ENSP00000312150 | angiopoietin-like 3 | tribbles homolog 1 (Drosophila); Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity | 0.510 |
CILP2 | ANGPTL3 | ENSP00000291495 | ENSP00000360170 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | angiopoietin-like 3 | 0.564 |
CILP2 | GALNT2 | ENSP00000291495 | ENSP00000355632 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | 0.563 |
CILP2 | MLXIPL | ENSP00000291495 | ENSP00000320886 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | MLX interacting protein-like | 0.660 |
CILP2 | MMAB | ENSP00000291495 | ENSP00000445920 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.471 |
CILP2 | PBX4 | ENSP00000291495 | ENSP00000251203 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | pre-B-cell leukemia homeobox 4 | 0.725 |
CILP2 | SORT1 | ENSP00000291495 | ENSP00000256637 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] | 0.480 |
CILP2 | TRIB1 | ENSP00000291495 | ENSP00000312150 | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | tribbles homolog 1 (Drosophila); Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity | 0.565 |
GALNT2 | ANGPTL3 | ENSP00000355632 | ENSP00000360170 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | angiopoietin-like 3 | 0.897 |
GALNT2 | CILP2 | ENSP00000355632 | ENSP00000291495 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | cartilage intermediate layer protein 2; May play a role in cartilage scaffolding (By similarity) | 0.563 |
GALNT2 | MLXIPL | ENSP00000355632 | ENSP00000320886 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | MLX interacting protein-like | 0.584 |
GALNT2 | MMAB | ENSP00000355632 | ENSP00000445920 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.629 |
GALNT2 | PBX4 | ENSP00000355632 | ENSP00000251203 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | pre-B-cell leukemia homeobox 4 | 0.561 |
GALNT2 | SORT1 | ENSP00000355632 | ENSP00000256637 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region | sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] | 0.533 |