DEFB103A protein (Homo sapiens) - STRING network view

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DEFB103A

defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed (67 aa)

Predicted Functional Partners:

DEFB1

0.788

DEFB128

0.649

DEFB4A

0.634

DEFA6

0.623

SPAG11B

0.602

DEFB127

0.585

DEFB103B

0.576

DEFA1B

0.509

DEFB119

0.483

DEFB124

0.483

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEFA1B	DEFB1	ENSP00000372136	ENSP00000297439	defensin, alpha 1B; Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane	defensin, beta 1; Has bactericidal activity (By similarity)	0.406
DEFA1B	DEFB103A	ENSP00000372136	ENSP00000320951	defensin, alpha 1B; Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	0.509
DEFA6	DEFB1	ENSP00000297436	ENSP00000297439	defensin, alpha 6, Paneth cell-specific; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1	defensin, beta 1; Has bactericidal activity (By similarity)	0.966
DEFA6	DEFB103A	ENSP00000297436	ENSP00000320951	defensin, alpha 6, Paneth cell-specific; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	0.623
DEFA6	DEFB103B	ENSP00000297436	ENSP00000324633	defensin, alpha 6, Paneth cell-specific; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1	defensin, beta 103B; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	0.472
DEFA6	DEFB4A	ENSP00000297436	ENSP00000303532	defensin, alpha 6, Paneth cell-specific; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1	defensin, beta 4A; Has antibacterial activity (Potential)	0.412
DEFB1	DEFA1B	ENSP00000297439	ENSP00000372136	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, alpha 1B; Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane	0.406
DEFB1	DEFA6	ENSP00000297439	ENSP00000297436	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, alpha 6, Paneth cell-specific; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1	0.966
DEFB1	DEFB103A	ENSP00000297439	ENSP00000320951	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	0.788
DEFB1	DEFB103B	ENSP00000297439	ENSP00000324633	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, beta 103B; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	0.783
DEFB1	DEFB119	ENSP00000297439	ENSP00000365492	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, beta 119; Has antibacterial activity (Potential)	0.486
DEFB1	DEFB124	ENSP00000297439	ENSP00000326309	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, beta 124; Has antibacterial activity (Potential)	0.568
DEFB1	DEFB4A	ENSP00000297439	ENSP00000303532	defensin, beta 1; Has bactericidal activity (By similarity)	defensin, beta 4A; Has antibacterial activity (Potential)	0.808
DEFB1	SPAG11B	ENSP00000297439	ENSP00000381480	defensin, beta 1; Has bactericidal activity (By similarity)	sperm associated antigen 11B	0.403
DEFB103A	DEFA1B	ENSP00000320951	ENSP00000372136	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	defensin, alpha 1B; Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane	0.509
DEFB103A	DEFA6	ENSP00000320951	ENSP00000297436	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	defensin, alpha 6, Paneth cell-specific; Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1	0.623
DEFB103A	DEFB1	ENSP00000320951	ENSP00000297439	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	defensin, beta 1; Has bactericidal activity (By similarity)	0.788
DEFB103A	DEFB103B	ENSP00000320951	ENSP00000324633	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	defensin, beta 103B; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	0.576
DEFB103A	DEFB119	ENSP00000320951	ENSP00000365492	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	defensin, beta 119; Has antibacterial activity (Potential)	0.483
DEFB103A	DEFB124	ENSP00000320951	ENSP00000326309	defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed	defensin, beta 124; Has antibacterial activity (Potential)	0.483

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