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STRINGSTRING
IL5 IL5 SLAMF1 SLAMF1 SIGLEC8 SIGLEC8 CHST1 CHST1 NCAM1 NCAM1 SIRPA SIRPA
"SIGLEC8" - sialic acid binding Ig-like lectin 8 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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protein homology
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SIGLEC8sialic acid binding Ig-like lectin 8; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface (499 aa)    
Predicted Functional Partners:
SIRPA
signal-regulatory protein alpha (504 aa)
         score_image       0.576
SLAMF1
signaling lymphocytic activation molecule family member 1; High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist- one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates (335 aa)
             score_image   0.511
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N- acetyllactosamine oligosaccharide chains att [...] (411 aa)
             score_image   0.416
NCAM1
neural cell adhesion molecule 1 (848 aa)
             score_image   0.412
IL5
interleukin 5 (colony-stimulating factor, eosinophil); Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells (134 aa)
             score_image   0.408
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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