TALDO1 protein (Homo sapiens) - STRING network view

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TALDO1

transaldolase 1; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) (337 aa)

Predicted Functional Partners:

TKT

0.998

TKTL2

0.986

GPI

0.976

PGM1

0.962

UBC

0.961

PFKL

0.948

PFKM

0.948

ALDOB

0.948

ALDOA

0.946

PFKP

0.944

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDOA	ALDOB	ENSP00000336927	ENSP00000363988	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	aldolase B, fructose-bisphosphate	0.829
ALDOA	GPI	ENSP00000336927	ENSP00000405573	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons	0.980
ALDOA	PFKL	ENSP00000336927	ENSP00000269848	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOA	PFKM	ENSP00000336927	ENSP00000345771	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.986
ALDOA	PFKP	ENSP00000336927	ENSP00000370517	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOA	PGM1	ENSP00000336927	ENSP00000360124	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphoglucomutase 1	0.930
ALDOA	TALDO1	ENSP00000336927	ENSP00000321259	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	transaldolase 1; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)	0.946
ALDOA	TKT	ENSP00000336927	ENSP00000405455	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	0.958
ALDOA	TKTL2	ENSP00000336927	ENSP00000280605	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	transketolase-like 2; Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis	0.937
ALDOA	UBC	ENSP00000336927	ENSP00000344818	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	ubiquitin C	0.999
ALDOB	ALDOA	ENSP00000363988	ENSP00000336927	aldolase B, fructose-bisphosphate	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	0.829
ALDOB	GPI	ENSP00000363988	ENSP00000405573	aldolase B, fructose-bisphosphate	glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons	0.980
ALDOB	PFKL	ENSP00000363988	ENSP00000269848	aldolase B, fructose-bisphosphate	phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOB	PFKM	ENSP00000363988	ENSP00000345771	aldolase B, fructose-bisphosphate	phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOB	PFKP	ENSP00000363988	ENSP00000370517	aldolase B, fructose-bisphosphate	phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOB	PGM1	ENSP00000363988	ENSP00000360124	aldolase B, fructose-bisphosphate	phosphoglucomutase 1	0.911
ALDOB	TALDO1	ENSP00000363988	ENSP00000321259	aldolase B, fructose-bisphosphate	transaldolase 1; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)	0.948
ALDOB	TKT	ENSP00000363988	ENSP00000405455	aldolase B, fructose-bisphosphate	transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	0.964
ALDOB	TKTL2	ENSP00000363988	ENSP00000280605	aldolase B, fructose-bisphosphate	transketolase-like 2; Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis	0.931
ALDOB	UBC	ENSP00000363988	ENSP00000344818	aldolase B, fructose-bisphosphate	ubiquitin C	0.752

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