node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC74B | DCBLD2 | ENSP00000308873 | ENSP00000321573 | coiled-coil domain containing 74B | discoidin, CUB and LCCL domain containing 2 | 0.472 |
CEP68 | DCBLD2 | ENSP00000367229 | ENSP00000321573 | centrosomal protein 68kDa | discoidin, CUB and LCCL domain containing 2 | 0.583 |
CEP68 | LRRC43 | ENSP00000367229 | ENSP00000344233 | centrosomal protein 68kDa | leucine rich repeat containing 43 | 0.633 |
CEP68 | UBC | ENSP00000367229 | ENSP00000344818 | centrosomal protein 68kDa | ubiquitin C | 0.483 |
CRKL | DCBLD2 | ENSP00000346300 | ENSP00000321573 | v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intracellular signals | discoidin, CUB and LCCL domain containing 2 | 0.587 |
CRKL | EGFR | ENSP00000346300 | ENSP00000275493 | v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intracellular signals | epidermal growth factor receptor | 0.988 |
CRKL | FYN | ENSP00000346300 | ENSP00000346671 | v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intracellular signals | FYN oncogene related to SRC, FGR, YES; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motilit [...] | 0.982 |
CRKL | UBC | ENSP00000346300 | ENSP00000344818 | v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intracellular signals | ubiquitin C | 0.927 |
DCBLD2 | CCDC74B | ENSP00000321573 | ENSP00000308873 | discoidin, CUB and LCCL domain containing 2 | coiled-coil domain containing 74B | 0.472 |
DCBLD2 | CEP68 | ENSP00000321573 | ENSP00000367229 | discoidin, CUB and LCCL domain containing 2 | centrosomal protein 68kDa | 0.583 |
DCBLD2 | CRKL | ENSP00000321573 | ENSP00000346300 | discoidin, CUB and LCCL domain containing 2 | v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intracellular signals | 0.587 |
DCBLD2 | EGFR | ENSP00000321573 | ENSP00000275493 | discoidin, CUB and LCCL domain containing 2 | epidermal growth factor receptor | 0.576 |
DCBLD2 | FYN | ENSP00000321573 | ENSP00000346671 | discoidin, CUB and LCCL domain containing 2 | FYN oncogene related to SRC, FGR, YES; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motilit [...] | 0.576 |
DCBLD2 | LRRC43 | ENSP00000321573 | ENSP00000344233 | discoidin, CUB and LCCL domain containing 2 | leucine rich repeat containing 43 | 0.568 |
DCBLD2 | SEMA4B | ENSP00000321573 | ENSP00000332204 | discoidin, CUB and LCCL domain containing 2 | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity) | 0.609 |
DCBLD2 | TRAF6 | ENSP00000321573 | ENSP00000337853 | discoidin, CUB and LCCL domain containing 2 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | 0.576 |
DCBLD2 | UBC | ENSP00000321573 | ENSP00000344818 | discoidin, CUB and LCCL domain containing 2 | ubiquitin C | 0.795 |
EGFR | CRKL | ENSP00000275493 | ENSP00000346300 | epidermal growth factor receptor | v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intracellular signals | 0.988 |
EGFR | DCBLD2 | ENSP00000275493 | ENSP00000321573 | epidermal growth factor receptor | discoidin, CUB and LCCL domain containing 2 | 0.576 |
EGFR | FYN | ENSP00000275493 | ENSP00000346671 | epidermal growth factor receptor | FYN oncogene related to SRC, FGR, YES; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motilit [...] | 0.932 |