ANKRD23 protein (Homo sapiens) - STRING network view

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ANKRD23

ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression (305 aa)

Predicted Functional Partners:

TTN

0.868

MYPN

0.792

YARS

0.722

MYOZ1

0.630

NEURL1B

0.585

NEURL

0.585

TCAP

0.555

HHATL

0.523

RFXANK

0.522

CAPN3

0.512

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD23	CAPN3	ENSP00000321679	ENSP00000380349	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	calpain 3, (p94); Calcium-regulated non-lysosomal thiol-protease	0.512
ANKRD23	HHATL	ENSP00000321679	ENSP00000310621	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	hedgehog acyltransferase-like; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN (By similarity)	0.523
ANKRD23	MYOZ1	ENSP00000321679	ENSP00000352272	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis	0.630
ANKRD23	MYPN	ENSP00000321679	ENSP00000351790	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines	0.792
ANKRD23	NEURL	ENSP00000321679	ENSP00000358795	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity)	0.585
ANKRD23	NEURL1B	ENSP00000321679	ENSP00000358815	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands	0.585
ANKRD23	RFXANK	ENSP00000321679	ENSP00000305071	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	regulatory factor X-associated ankyrin-containing protein; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes	0.522
ANKRD23	TCAP	ENSP00000321679	ENSP00000312624	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	titin-cap; Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk	0.555
ANKRD23	TTN	ENSP00000321679	ENSP00000343764	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	titin	0.868
ANKRD23	YARS	ENSP00000321679	ENSP00000362576	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)	0.722
CAPN3	ANKRD23	ENSP00000380349	ENSP00000321679	calpain 3, (p94); Calcium-regulated non-lysosomal thiol-protease	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	0.512
CAPN3	MYPN	ENSP00000380349	ENSP00000351790	calpain 3, (p94); Calcium-regulated non-lysosomal thiol-protease	myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines	0.472
CAPN3	TCAP	ENSP00000380349	ENSP00000312624	calpain 3, (p94); Calcium-regulated non-lysosomal thiol-protease	titin-cap; Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk	0.634
CAPN3	TTN	ENSP00000380349	ENSP00000343764	calpain 3, (p94); Calcium-regulated non-lysosomal thiol-protease	titin	0.998
HHATL	ANKRD23	ENSP00000310621	ENSP00000321679	hedgehog acyltransferase-like; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN (By similarity)	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	0.523
HHATL	MYOZ1	ENSP00000310621	ENSP00000352272	hedgehog acyltransferase-like; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN (By similarity)	myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis	0.448
MYOZ1	ANKRD23	ENSP00000352272	ENSP00000321679	myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis	ankyrin repeat domain 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression	0.630
MYOZ1	HHATL	ENSP00000352272	ENSP00000310621	myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis	hedgehog acyltransferase-like; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN (By similarity)	0.448
MYOZ1	MYPN	ENSP00000352272	ENSP00000351790	myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis	myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines	0.597
MYOZ1	TCAP	ENSP00000352272	ENSP00000312624	myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis	titin-cap; Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk	0.934

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