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STRINGSTRING
COG7 COG7 CC2D1A CC2D1A UBC UBC C6orf70 C6orf70 C10orf118 C10orf118 FHAD1 FHAD1 TMEM101 TMEM101 HEATR7A HEATR7A SNX29 SNX29 MIER2 MIER2 SUSD5 SUSD5
"HEATR7A" - HEAT repeat containing 7A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEATR7AHEAT repeat containing 7A (1641 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.721
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1 (1453 aa)
            score_image   0.647
SNX29
sorting nexin 29 (375 aa)
            score_image   0.585
TMEM101
transmembrane protein 101; May activate NF-kappa-B signaling pathways (257 aa)
            score_image   0.539
C6orf70
chromosome 6 open reading frame 70 (678 aa)
            score_image   0.507
C10orf118
chromosome 10 open reading frame 118 (898 aa)
            score_image   0.481
SUSD5
sushi domain containing 5 (629 aa)
            score_image   0.477
MIER2
mesoderm induction early response 1, family member 2; Transcriptional repressor (By similarity) (545 aa)
            score_image   0.472
COG7
component of oligomeric golgi complex 7; Required for normal Golgi function (By similarity) (770 aa)
            score_image   0.434
CC2D1A
coiled-coil and C2 domain containing 1A; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasm [...] (951 aa)
            score_image   0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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