node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A4GALT | FAIM2 | ENSP00000249005 | ENSP00000321951 | alpha 1,4-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | 0.810 |
AQP1 | FAIM2 | ENSP00000311165 | ENSP00000321951 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | 0.606 |
BAX | FAIM2 | ENSP00000293288 | ENSP00000321951 | BCL2-associated X protein | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | 0.802 |
BAX | FAS | ENSP00000293288 | ENSP00000347979 | BCL2-associated X protein | Fas (TNF receptor superfamily, member 6) | 0.808 |
BCDIN3D | FAIM2 | ENSP00000335201 | ENSP00000321951 | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | 0.689 |
BCDIN3D | GNPDA2 | ENSP00000335201 | ENSP00000295448 | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | glucosamine-6-phosphate deaminase 2 | 0.751 |
BCDIN3D | KCTD15 | ENSP00000335201 | ENSP00000394390 | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | potassium channel tetramerisation domain containing 15 | 0.716 |
BCDIN3D | MTCH2 | ENSP00000335201 | ENSP00000303222 | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | mitochondrial carrier 2; The substrate transported is not yet known. Induces mitochondrial depolarization | 0.669 |
BCDIN3D | SEC16B | ENSP00000335201 | ENSP00000308339 | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | SEC16 homolog B (S. cerevisiae); Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization | 0.761 |
BCDIN3D | TMEM18 | ENSP00000335201 | ENSP00000281017 | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) | 0.752 |
FAIM2 | A4GALT | ENSP00000321951 | ENSP00000249005 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | alpha 1,4-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins | 0.810 |
FAIM2 | AQP1 | ENSP00000321951 | ENSP00000311165 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | 0.606 |
FAIM2 | BAX | ENSP00000321951 | ENSP00000293288 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | BCL2-associated X protein | 0.802 |
FAIM2 | BCDIN3D | ENSP00000321951 | ENSP00000335201 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | BCDIN3 domain containing; O-methyltransferase that specifically dimethylates the 5’ monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5’ monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing- methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs | 0.689 |
FAIM2 | FAS | ENSP00000321951 | ENSP00000347979 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | Fas (TNF receptor superfamily, member 6) | 0.976 |
FAIM2 | GNPDA2 | ENSP00000321951 | ENSP00000295448 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | glucosamine-6-phosphate deaminase 2 | 0.732 |
FAIM2 | KCTD15 | ENSP00000321951 | ENSP00000394390 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | potassium channel tetramerisation domain containing 15 | 0.669 |
FAIM2 | MTCH2 | ENSP00000321951 | ENSP00000303222 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | mitochondrial carrier 2; The substrate transported is not yet known. Induces mitochondrial depolarization | 0.725 |
FAIM2 | SEC16B | ENSP00000321951 | ENSP00000308339 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | SEC16 homolog B (S. cerevisiae); Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization | 0.722 |
FAIM2 | TMEM18 | ENSP00000321951 | ENSP00000281017 | Fas apoptotic inhibitory molecule 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development | transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) | 0.708 |