| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EBNA1BP2 | FBL | ENSP00000407323 | ENSP00000221801 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | 0.980 |
| EBNA1BP2 | FTSJ3 | ENSP00000407323 | ENSP00000396673 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.999 |
| EBNA1BP2 | GNL3 | ENSP00000407323 | ENSP00000395772 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) | 0.998 |
| EBNA1BP2 | MKI67IP | ENSP00000407323 | ENSP00000285814 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.993 |
| EBNA1BP2 | MRTO4 | ENSP00000407323 | ENSP00000364320 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | mRNA turnover 4 homolog (S. cerevisiae); Involved in mRNA turnover and ribosome assembly (By similarity) | 0.909 |
| EBNA1BP2 | NOC3L | ENSP00000407323 | ENSP00000360412 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) | 0.962 |
| EBNA1BP2 | NOP2 | ENSP00000407323 | ENSP00000382392 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.999 |
| EBNA1BP2 | RPF2 | ENSP00000407323 | ENSP00000402338 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | ribosome production factor 2 homolog (S. cerevisiae) | 0.999 |
| EBNA1BP2 | RPL5 | ENSP00000407323 | ENSP00000359345 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | ribosomal protein L5; Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA | 0.954 |
| EBNA1BP2 | RRS1 | ENSP00000407323 | ENSP00000322396 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) | 0.999 |
| FBL | EBNA1BP2 | ENSP00000221801 | ENSP00000407323 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | 0.980 |
| FBL | FTSJ3 | ENSP00000221801 | ENSP00000396673 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.982 |
| FBL | GNL3 | ENSP00000221801 | ENSP00000395772 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) | 0.987 |
| FBL | MKI67IP | ENSP00000221801 | ENSP00000285814 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.996 |
| FBL | MRTO4 | ENSP00000221801 | ENSP00000364320 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | mRNA turnover 4 homolog (S. cerevisiae); Involved in mRNA turnover and ribosome assembly (By similarity) | 0.956 |
| FBL | NOC3L | ENSP00000221801 | ENSP00000360412 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) | 0.437 |
| FBL | NOP2 | ENSP00000221801 | ENSP00000382392 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.995 |
| FBL | RPF2 | ENSP00000221801 | ENSP00000402338 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | ribosome production factor 2 homolog (S. cerevisiae) | 0.844 |
| FBL | RPL5 | ENSP00000221801 | ENSP00000359345 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | ribosomal protein L5; Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA | 0.960 |
| FBL | RRS1 | ENSP00000221801 | ENSP00000322396 | fibrillarin; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) | 0.981 |
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