node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf173 | CCDC66 | ENSP00000322609 | ENSP00000378167 | chromosome 1 open reading frame 173 | coiled-coil domain containing 66 | 0.499 |
C1orf173 | CRISPLD2 | ENSP00000322609 | ENSP00000262424 | chromosome 1 open reading frame 173 | cysteine-rich secretory protein LCCL domain containing 2; Promotes matrix assembly (By similarity) | 0.414 |
C1orf173 | GIMAP4 | ENSP00000322609 | ENSP00000255945 | chromosome 1 open reading frame 173 | GTPase, IMAP family member 4; May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium | 0.505 |
C1orf173 | PPP6R1 | ENSP00000322609 | ENSP00000414202 | chromosome 1 open reading frame 173 | protein phosphatase 6, regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha | 0.450 |
C1orf173 | SLC45A4 | ENSP00000322609 | ENSP00000024061 | chromosome 1 open reading frame 173 | solute carrier family 45, member 4 | 0.580 |
C1orf173 | TAF5L | ENSP00000322609 | ENSP00000258281 | chromosome 1 open reading frame 173 | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex | 0.499 |
C1orf173 | TLE3 | ENSP00000322609 | ENSP00000452871 | chromosome 1 open reading frame 173 | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) | 0.566 |
C1orf173 | TTC23 | ENSP00000322609 | ENSP00000262074 | chromosome 1 open reading frame 173 | tetratricopeptide repeat domain 23 | 0.721 |
CCDC66 | C1orf173 | ENSP00000378167 | ENSP00000322609 | coiled-coil domain containing 66 | chromosome 1 open reading frame 173 | 0.499 |
CCDC66 | SLC45A4 | ENSP00000378167 | ENSP00000024061 | coiled-coil domain containing 66 | solute carrier family 45, member 4 | 0.454 |
CCDC66 | TTC23 | ENSP00000378167 | ENSP00000262074 | coiled-coil domain containing 66 | tetratricopeptide repeat domain 23 | 0.459 |
CRISPLD2 | C1orf173 | ENSP00000262424 | ENSP00000322609 | cysteine-rich secretory protein LCCL domain containing 2; Promotes matrix assembly (By similarity) | chromosome 1 open reading frame 173 | 0.414 |
GIMAP4 | C1orf173 | ENSP00000255945 | ENSP00000322609 | GTPase, IMAP family member 4; May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium | chromosome 1 open reading frame 173 | 0.505 |
PPP6R1 | C1orf173 | ENSP00000414202 | ENSP00000322609 | protein phosphatase 6, regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha | chromosome 1 open reading frame 173 | 0.450 |
PPP6R1 | TTC23 | ENSP00000414202 | ENSP00000262074 | protein phosphatase 6, regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha | tetratricopeptide repeat domain 23 | 0.404 |
SLC45A4 | C1orf173 | ENSP00000024061 | ENSP00000322609 | solute carrier family 45, member 4 | chromosome 1 open reading frame 173 | 0.580 |
SLC45A4 | CCDC66 | ENSP00000024061 | ENSP00000378167 | solute carrier family 45, member 4 | coiled-coil domain containing 66 | 0.454 |
SLC45A4 | TTC23 | ENSP00000024061 | ENSP00000262074 | solute carrier family 45, member 4 | tetratricopeptide repeat domain 23 | 0.539 |
TAF5L | C1orf173 | ENSP00000258281 | ENSP00000322609 | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex | chromosome 1 open reading frame 173 | 0.499 |
TLE3 | C1orf173 | ENSP00000452871 | ENSP00000322609 | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) | chromosome 1 open reading frame 173 | 0.566 |