node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD10 | CATSPERB | ENSP00000273359 | ENSP00000256343 | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | 0.509 |
ABHD10 | CCDC135 | ENSP00000273359 | ENSP00000353942 | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | coiled-coil domain containing 135; Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility (By similarity) | 0.520 |
ABHD10 | MYCBPAP | ENSP00000273359 | ENSP00000323184 | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | 0.540 |
ABHD10 | OAZ3 | ENSP00000273359 | ENSP00000415904 | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells | 0.475 |
AKAP1 | MYCBP | ENSP00000337736 | ENSP00000380702 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | c-myc binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC | 0.997 |
AKAP1 | MYCBPAP | ENSP00000337736 | ENSP00000323184 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | 0.756 |
AKAP1 | PRKAR2A | ENSP00000337736 | ENSP00000265563 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.999 |
CATSPERB | ABHD10 | ENSP00000256343 | ENSP00000273359 | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | 0.509 |
CATSPERB | CCDC135 | ENSP00000256343 | ENSP00000353942 | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | coiled-coil domain containing 135; Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility (By similarity) | 0.554 |
CATSPERB | MYCBPAP | ENSP00000256343 | ENSP00000323184 | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | 0.529 |
CATSPERB | OAZ3 | ENSP00000256343 | ENSP00000415904 | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells | 0.481 |
CCDC135 | ABHD10 | ENSP00000353942 | ENSP00000273359 | coiled-coil domain containing 135; Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility (By similarity) | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | 0.520 |
CCDC135 | CATSPERB | ENSP00000353942 | ENSP00000256343 | coiled-coil domain containing 135; Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility (By similarity) | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | 0.554 |
CCDC135 | MYCBPAP | ENSP00000353942 | ENSP00000323184 | coiled-coil domain containing 135; Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility (By similarity) | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | 0.537 |
CCDC135 | OAZ3 | ENSP00000353942 | ENSP00000415904 | coiled-coil domain containing 135; Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility (By similarity) | ornithine decarboxylase antizyme 3; Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells | 0.460 |
MYCBP | AKAP1 | ENSP00000380702 | ENSP00000337736 | c-myc binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | 0.997 |
MYCBP | MYCBPAP | ENSP00000380702 | ENSP00000323184 | c-myc binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | 0.973 |
MYCBPAP | ABHD10 | ENSP00000323184 | ENSP00000273359 | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate | 0.540 |
MYCBPAP | AKAP1 | ENSP00000323184 | ENSP00000337736 | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | 0.756 |
MYCBPAP | CATSPERB | ENSP00000323184 | ENSP00000256343 | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | catsper channel auxiliary subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity) | 0.529 |