| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C12orf29 | CEP290 | ENSP00000349358 | ENSP00000448012 | chromosome 12 open reading frame 29 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.430 |
| C12orf29 | POC1B | ENSP00000349358 | ENSP00000323302 | chromosome 12 open reading frame 29 | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.660 |
| C12orf29 | RASSF9 | ENSP00000349358 | ENSP00000354884 | chromosome 12 open reading frame 29 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity) | 0.659 |
| CEP290 | C12orf29 | ENSP00000448012 | ENSP00000349358 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | chromosome 12 open reading frame 29 | 0.430 |
| CEP290 | CEP97 | ENSP00000448012 | ENSP00000342510 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | centrosomal protein 97kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome | 0.844 |
| CEP290 | POC1B | ENSP00000448012 | ENSP00000323302 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.484 |
| CEP290 | RASSF9 | ENSP00000448012 | ENSP00000354884 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity) | 0.445 |
| CEP97 | CEP290 | ENSP00000342510 | ENSP00000448012 | centrosomal protein 97kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.844 |
| CEP97 | CETN2 | ENSP00000342510 | ENSP00000359300 | centrosomal protein 97kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome | centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110 | 0.453 |
| CEP97 | POC1B | ENSP00000342510 | ENSP00000323302 | centrosomal protein 97kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.555 |
| CETN2 | CEP97 | ENSP00000359300 | ENSP00000342510 | centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110 | centrosomal protein 97kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome | 0.453 |
| CETN2 | POC1B | ENSP00000359300 | ENSP00000323302 | centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110 | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.442 |
| GNB1L | POC1B | ENSP00000331313 | ENSP00000323302 | guanine nucleotide binding protein (G protein), beta polypeptide 1-like | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.428 |
| IFT172 | POC1B | ENSP00000260570 | ENSP00000323302 | intraflagellar transport 172 homolog (Chlamydomonas); Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity) | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.456 |
| PACRG | POC1B | ENSP00000337946 | ENSP00000323302 | PARK2 co-regulated; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.531 |
| PACRG | WDR67 | ENSP00000337946 | ENSP00000287380 | PARK2 co-regulated; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease | WD repeat domain 67 | 0.596 |
| PACRGL | POC1B | ENSP00000295290 | ENSP00000323302 | PARK2 co-regulated-like | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.485 |
| PACRGL | WDR67 | ENSP00000295290 | ENSP00000287380 | PARK2 co-regulated-like | WD repeat domain 67 | 0.596 |
| POC1B | C12orf29 | ENSP00000323302 | ENSP00000349358 | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | chromosome 12 open reading frame 29 | 0.660 |
| POC1B | CEP290 | ENSP00000323302 | ENSP00000448012 | POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.484 |
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