node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B9D1 | BAIAP3 | ENSP00000261499 | ENSP00000324510 | B9 protein domain 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) | BAI1-associated protein 3 | 0.502 |
B9D1 | CLUAP1 | ENSP00000261499 | ENSP00000460850 | B9 protein domain 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | 0.566 |
B9D1 | RBKS | ENSP00000261499 | ENSP00000306817 | B9 protein domain 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) | ribokinase | 0.507 |
BAI1 | BAIAP3 | ENSP00000313046 | ENSP00000324510 | brain-specific angiogenesis inhibitor 1; Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain | BAI1-associated protein 3 | 0.850 |
BAIAP3 | B9D1 | ENSP00000324510 | ENSP00000261499 | BAI1-associated protein 3 | B9 protein domain 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) | 0.502 |
BAIAP3 | BAI1 | ENSP00000324510 | ENSP00000313046 | BAI1-associated protein 3 | brain-specific angiogenesis inhibitor 1; Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain | 0.850 |
BAIAP3 | CLUAP1 | ENSP00000324510 | ENSP00000460850 | BAI1-associated protein 3 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | 0.593 |
BAIAP3 | CMBL | ENSP00000324510 | ENSP00000296658 | BAI1-associated protein 3 | carboxymethylenebutenolidase homolog (Pseudomonas); Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin | 0.443 |
BAIAP3 | CRAMP1L | ENSP00000324510 | ENSP00000293925 | BAI1-associated protein 3 | Crm, cramped-like (Drosophila) | 0.453 |
BAIAP3 | FIGLA | ENSP00000324510 | ENSP00000333097 | BAI1-associated protein 3 | folliculogenesis specific basic helix-loop-helix; Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian develop [...] | 0.527 |
BAIAP3 | IPO13 | ENSP00000324510 | ENSP00000361418 | BAI1-associated protein 3 | importin 13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | 0.808 |
BAIAP3 | RBBP6 | ENSP00000324510 | ENSP00000317872 | BAI1-associated protein 3 | retinoblastoma binding protein 6 | 0.451 |
BAIAP3 | RBKS | ENSP00000324510 | ENSP00000306817 | BAI1-associated protein 3 | ribokinase | 0.506 |
BAIAP3 | SCTR | ENSP00000324510 | ENSP00000019103 | BAI1-associated protein 3 | secretin receptor; This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | 0.742 |
CLUAP1 | B9D1 | ENSP00000460850 | ENSP00000261499 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | B9 protein domain 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) | 0.566 |
CLUAP1 | BAIAP3 | ENSP00000460850 | ENSP00000324510 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | BAI1-associated protein 3 | 0.593 |
CLUAP1 | RBKS | ENSP00000460850 | ENSP00000306817 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | ribokinase | 0.583 |
CMBL | BAIAP3 | ENSP00000296658 | ENSP00000324510 | carboxymethylenebutenolidase homolog (Pseudomonas); Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin | BAI1-associated protein 3 | 0.443 |
CRAMP1L | BAIAP3 | ENSP00000293925 | ENSP00000324510 | Crm, cramped-like (Drosophila) | BAI1-associated protein 3 | 0.453 |
FIGLA | BAIAP3 | ENSP00000333097 | ENSP00000324510 | folliculogenesis specific basic helix-loop-helix; Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian develop [...] | BAI1-associated protein 3 | 0.527 |