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FKRP FKRP POMGNT1 POMGNT1 POMT1 POMT1 FKTN FKTN PI16 PI16 POMT2 POMT2 GYLTL1B GYLTL1B GJA5 GJA5 LMTK2 LMTK2 SLITRK1 SLITRK1 HDC HDC
"GYLTL1B" - glycosyltransferase-like 1B in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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experimentally determined
Predicted Interactions
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protein homology
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GYLTL1Bglycosyltransferase-like 1B; Glycosyltransferase which participates in glycosylation of alpha-dystroglycan. May carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. Has a higher activity toward alpha-dystroglycan than LARGE (721 aa)    
Predicted Functional Partners:
PI16
peptidase inhibitor 16; Putative serine protease inhibitor (By similarity) (463 aa)
            score_image   0.801
LMTK2
lemur tyrosine kinase 2; Phosphorylates PPP1C, phosphorylase b and CFTR (1503 aa)
            score_image   0.750
POMT2
protein-O-mannosyltransferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient (750 aa)
            score_image   0.718
HDC
histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine (662 aa)
            score_image   0.680
POMT1
protein-O-mannosyltransferase 1 (747 aa)
            score_image   0.674
GJA5
gap junction protein, alpha 5, 40kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (358 aa)
            score_image   0.649
POMGNT1
protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O- Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity (660 aa)
            score_image   0.612
SLITRK1
SLIT and NTRK-like family, member 1; Enhances neuronal dendrite outgrowth (696 aa)
            score_image   0.610
FKTN
fukutin; May be a glycosyltransferase which participates in glycosylation of alpha-dystroglycan/DAG1. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development (461 aa)
            score_image   0.609
FKRP
fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) (495 aa)
            score_image   0.606
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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