node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM150A | FAM78A | ENSP00000351345 | ENSP00000361345 | family with sequence similarity 150, member A | family with sequence similarity 78, member A | 0.635 |
FAM150A | PCDHAC1 | ENSP00000351345 | ENSP00000253807 | family with sequence similarity 150, member A | protocadherin alpha subfamily C, 1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | 0.728 |
FAM150A | RIMS4 | ENSP00000351345 | ENSP00000439287 | family with sequence similarity 150, member A | regulating synaptic membrane exocytosis 4; Regulates synaptic membrane exocytosis (By similarity) | 0.634 |
FAM150A | ZNF540 | ENSP00000351345 | ENSP00000324598 | family with sequence similarity 150, member A | zinc finger protein 540; May act as a transcriptional repressor | 0.659 |
FAM78A | FAM150A | ENSP00000361345 | ENSP00000351345 | family with sequence similarity 78, member A | family with sequence similarity 150, member A | 0.635 |
FAM78A | PCDHAC1 | ENSP00000361345 | ENSP00000253807 | family with sequence similarity 78, member A | protocadherin alpha subfamily C, 1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | 0.635 |
FAM78A | RIMS4 | ENSP00000361345 | ENSP00000439287 | family with sequence similarity 78, member A | regulating synaptic membrane exocytosis 4; Regulates synaptic membrane exocytosis (By similarity) | 0.507 |
FAM78A | ZNF540 | ENSP00000361345 | ENSP00000324598 | family with sequence similarity 78, member A | zinc finger protein 540; May act as a transcriptional repressor | 0.561 |
FBXL19 | UTY | ENSP00000369666 | ENSP00000328939 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked; Histone demethylase (By similarity) | 0.615 |
FBXL19 | ZNF540 | ENSP00000369666 | ENSP00000324598 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 540; May act as a transcriptional repressor | 0.501 |
KDM2A | UTY | ENSP00000432786 | ENSP00000328939 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked; Histone demethylase (By similarity) | 0.615 |
KDM2A | ZNF540 | ENSP00000432786 | ENSP00000324598 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 540; May act as a transcriptional repressor | 0.501 |
KDM2B | UTY | ENSP00000366271 | ENSP00000328939 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked; Histone demethylase (By similarity) | 0.615 |
KDM2B | ZNF540 | ENSP00000366271 | ENSP00000324598 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 540; May act as a transcriptional repressor | 0.501 |
PCDHAC1 | FAM150A | ENSP00000253807 | ENSP00000351345 | protocadherin alpha subfamily C, 1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | family with sequence similarity 150, member A | 0.728 |
PCDHAC1 | FAM78A | ENSP00000253807 | ENSP00000361345 | protocadherin alpha subfamily C, 1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | family with sequence similarity 78, member A | 0.635 |
PCDHAC1 | RIMS4 | ENSP00000253807 | ENSP00000439287 | protocadherin alpha subfamily C, 1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | regulating synaptic membrane exocytosis 4; Regulates synaptic membrane exocytosis (By similarity) | 0.635 |
PCDHAC1 | ZNF540 | ENSP00000253807 | ENSP00000324598 | protocadherin alpha subfamily C, 1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | zinc finger protein 540; May act as a transcriptional repressor | 0.660 |
PTPN23 | ZNF540 | ENSP00000265562 | ENSP00000324598 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis | zinc finger protein 540; May act as a transcriptional repressor | 0.476 |
RIMS4 | FAM150A | ENSP00000439287 | ENSP00000351345 | regulating synaptic membrane exocytosis 4; Regulates synaptic membrane exocytosis (By similarity) | family with sequence similarity 150, member A | 0.634 |