node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACADM | ACOX1 | ENSP00000409612 | ENSP00000293217 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | acyl-CoA oxidase 1, palmitoyl | 0.643 |
ACADM | ECI1 | ENSP00000409612 | ENSP00000301729 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | enoyl-CoA delta isomerase 1; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species | 0.816 |
ACADM | EHHADH | ENSP00000409612 | ENSP00000231887 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.993 |
ACADM | HADH | ENSP00000409612 | ENSP00000385638 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | 0.783 |
ACADM | HADHA | ENSP00000409612 | ENSP00000370023 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 0.994 |
ACADM | HADHB | ENSP00000409612 | ENSP00000325136 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 0.984 |
ACADM | HMGCS2 | ENSP00000409612 | ENSP00000358414 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase | 0.475 |
ACADS | ECI1 | ENSP00000242592 | ENSP00000301729 | acyl-CoA dehydrogenase, C-2 to C-3 short chain | enoyl-CoA delta isomerase 1; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species | 0.747 |
ACADS | EHHADH | ENSP00000242592 | ENSP00000231887 | acyl-CoA dehydrogenase, C-2 to C-3 short chain | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.989 |
ACADS | HADH | ENSP00000242592 | ENSP00000385638 | acyl-CoA dehydrogenase, C-2 to C-3 short chain | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | 0.833 |
ACADS | HADHA | ENSP00000242592 | ENSP00000370023 | acyl-CoA dehydrogenase, C-2 to C-3 short chain | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 0.992 |
ACADS | HADHB | ENSP00000242592 | ENSP00000325136 | acyl-CoA dehydrogenase, C-2 to C-3 short chain | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 0.977 |
ACADVL | ACOX1 | ENSP00000349297 | ENSP00000293217 | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | acyl-CoA oxidase 1, palmitoyl | 0.555 |
ACADVL | ECI1 | ENSP00000349297 | ENSP00000301729 | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | enoyl-CoA delta isomerase 1; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species | 0.746 |
ACADVL | EHHADH | ENSP00000349297 | ENSP00000231887 | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.989 |
ACADVL | HADH | ENSP00000349297 | ENSP00000385638 | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | 0.841 |
ACADVL | HADHA | ENSP00000349297 | ENSP00000370023 | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 0.994 |
ACADVL | HADHB | ENSP00000349297 | ENSP00000325136 | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 0.981 |
ACOX1 | ACADM | ENSP00000293217 | ENSP00000409612 | acyl-CoA oxidase 1, palmitoyl | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | 0.643 |
ACOX1 | ACADVL | ENSP00000293217 | ENSP00000349297 | acyl-CoA oxidase 1, palmitoyl | acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | 0.555 |