node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL14A1 | ENG | ENSP00000297848 | ENSP00000362299 | collagen, type XIV, alpha 1 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | 0.757 |
COL14A1 | ESD | ENSP00000297848 | ENSP00000367992 | collagen, type XIV, alpha 1 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | 0.659 |
COL14A1 | LIAS | ENSP00000297848 | ENSP00000261434 | collagen, type XIV, alpha 1 | lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) | 0.754 |
COL14A1 | PARL | ENSP00000297848 | ENSP00000325421 | collagen, type XIV, alpha 1 | presenilin associated, rhomboid-like; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain | 0.824 |
COL14A1 | SH3GL1 | ENSP00000297848 | ENSP00000269886 | collagen, type XIV, alpha 1 | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | 0.725 |
COL14A1 | UBXN11 | ENSP00000297848 | ENSP00000363338 | collagen, type XIV, alpha 1 | UBX domain protein 11 | 0.772 |
ENG | COL14A1 | ENSP00000362299 | ENSP00000297848 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | collagen, type XIV, alpha 1 | 0.757 |
ENG | ESD | ENSP00000362299 | ENSP00000367992 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | 0.700 |
ENG | LIAS | ENSP00000362299 | ENSP00000261434 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) | 0.725 |
ENG | PARL | ENSP00000362299 | ENSP00000325421 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | presenilin associated, rhomboid-like; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain | 0.822 |
ENG | PTPRF | ENSP00000362299 | ENSP00000353030 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | protein tyrosine phosphatase, receptor type, F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) | 0.725 |
ENG | SH3GL1 | ENSP00000362299 | ENSP00000269886 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | 0.757 |
ENG | UBXN11 | ENSP00000362299 | ENSP00000363338 | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | UBX domain protein 11 | 0.810 |
ESD | COL14A1 | ENSP00000367992 | ENSP00000297848 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | collagen, type XIV, alpha 1 | 0.659 |
ESD | ENG | ENSP00000367992 | ENSP00000362299 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | endoglin; Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors | 0.700 |
ESD | LIAS | ENSP00000367992 | ENSP00000261434 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) | 0.648 |
ESD | PARL | ENSP00000367992 | ENSP00000325421 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | presenilin associated, rhomboid-like; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain | 0.879 |
ESD | PTPRF | ENSP00000367992 | ENSP00000353030 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | protein tyrosine phosphatase, receptor type, F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) | 0.725 |
ESD | SH3GL1 | ENSP00000367992 | ENSP00000269886 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | 0.720 |
ESD | UBXN11 | ENSP00000367992 | ENSP00000363338 | esterase D; Serine hydrolase involved in the detoxification of formaldehyde | UBX domain protein 11 | 0.647 |