CLVS1 protein (Homo sapiens) - STRING network view

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CLVS1

clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (354 aa)

Predicted Functional Partners:

SACM1L

0.575

NKAIN3

0.568

PLD1

0.547

PLD2

0.547

C8orf34

0.535

OR52H1

0.506

PCSK2

0.498

UBQLNL

0.487

FOXI2

0.475

SPAG9

0.468

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C8orf34	CLVS1	ENSP00000427820	ENSP00000325506	chromosome 8 open reading frame 34	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.535
C8orf34	NKAIN3	ENSP00000427820	ENSP00000333627	chromosome 8 open reading frame 34	Na+/K+ transporting ATPase interacting 3	0.655
CLVS1	C8orf34	ENSP00000325506	ENSP00000427820	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	chromosome 8 open reading frame 34	0.535
CLVS1	FOXI2	ENSP00000325506	ENSP00000373572	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	forkhead box I2; Possible transcriptional activator (By similarity)	0.475
CLVS1	NKAIN3	ENSP00000325506	ENSP00000333627	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Na+/K+ transporting ATPase interacting 3	0.568
CLVS1	OR52H1	ENSP00000325506	ENSP00000326259	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	olfactory receptor, family 52, subfamily H, member 1; Odorant receptor (Potential)	0.506
CLVS1	PCSK2	ENSP00000325506	ENSP00000262545	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	proprotein convertase subtilisin/kexin type 2	0.498
CLVS1	PLD1	ENSP00000325506	ENSP00000342793	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	phospholipase D1, phosphatidylcholine-specific; Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity)	0.547
CLVS1	PLD2	ENSP00000325506	ENSP00000263088	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity)	0.547
CLVS1	SACM1L	ENSP00000325506	ENSP00000373713	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	SAC1 suppressor of actin mutations 1-like (yeast); Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Has low activity towards PtdIns(3,5)P2 (By similarity)	0.575
CLVS1	SPAG9	ENSP00000325506	ENSP00000262013	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	sperm associated antigen 9	0.468
CLVS1	UBQLNL	ENSP00000325506	ENSP00000369531	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	ubiquilin-like	0.487
FOXI2	CLVS1	ENSP00000373572	ENSP00000325506	forkhead box I2; Possible transcriptional activator (By similarity)	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.475
NKAIN3	C8orf34	ENSP00000333627	ENSP00000427820	Na+/K+ transporting ATPase interacting 3	chromosome 8 open reading frame 34	0.655
NKAIN3	CLVS1	ENSP00000333627	ENSP00000325506	Na+/K+ transporting ATPase interacting 3	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.568
OR52H1	CLVS1	ENSP00000326259	ENSP00000325506	olfactory receptor, family 52, subfamily H, member 1; Odorant receptor (Potential)	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.506
OR52H1	UBQLNL	ENSP00000326259	ENSP00000369531	olfactory receptor, family 52, subfamily H, member 1; Odorant receptor (Potential)	ubiquilin-like	0.658
PCSK2	CLVS1	ENSP00000262545	ENSP00000325506	proprotein convertase subtilisin/kexin type 2	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.498
PLD1	CLVS1	ENSP00000342793	ENSP00000325506	phospholipase D1, phosphatidylcholine-specific; Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity)	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.547
PLD2	CLVS1	ENSP00000263088	ENSP00000325506	phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity)	clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.547

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