node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHST11 | RIMS2 | ENSP00000305725 | ENSP00000384892 | carbohydrate (chondroitin 4) sulfotransferase 11; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.483 |
CHST11 | SLC41A3 | ENSP00000305725 | ENSP00000326070 | carbohydrate (chondroitin 4) sulfotransferase 11; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor | solute carrier family 41, member 3 | 0.483 |
CHST13 | RIMS2 | ENSP00000317404 | ENSP00000384892 | carbohydrate (chondroitin 4) sulfotransferase 13; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.602 |
CHST13 | SLC41A3 | ENSP00000317404 | ENSP00000326070 | carbohydrate (chondroitin 4) sulfotransferase 13; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan | solute carrier family 41, member 3 | 0.680 |
CNNM1 | MRS2 | ENSP00000349147 | ENSP00000367637 | cyclin M1; Probable metal transporter (By similarity) | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | 0.559 |
CNNM1 | NIPA1 | ENSP00000349147 | ENSP00000337452 | cyclin M1; Probable metal transporter (By similarity) | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.491 |
CNNM1 | SLC41A3 | ENSP00000349147 | ENSP00000326070 | cyclin M1; Probable metal transporter (By similarity) | solute carrier family 41, member 3 | 0.483 |
CNNM2 | MMGT1 | ENSP00000358894 | ENSP00000306220 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | 0.566 |
CNNM2 | MRS2 | ENSP00000358894 | ENSP00000367637 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | 0.787 |
CNNM2 | NIPA1 | ENSP00000358894 | ENSP00000337452 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.488 |
CNNM2 | SLC41A3 | ENSP00000358894 | ENSP00000326070 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | solute carrier family 41, member 3 | 0.491 |
MMGT1 | CNNM2 | ENSP00000306220 | ENSP00000358894 | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | 0.566 |
MMGT1 | NIPA1 | ENSP00000306220 | ENSP00000337452 | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.642 |
MMGT1 | SLC41A3 | ENSP00000306220 | ENSP00000326070 | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | solute carrier family 41, member 3 | 0.621 |
MRS2 | CNNM1 | ENSP00000367637 | ENSP00000349147 | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | cyclin M1; Probable metal transporter (By similarity) | 0.559 |
MRS2 | CNNM2 | ENSP00000367637 | ENSP00000358894 | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | 0.787 |
MRS2 | NIPA1 | ENSP00000367637 | ENSP00000337452 | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.508 |
MRS2 | SLC41A3 | ENSP00000367637 | ENSP00000326070 | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | solute carrier family 41, member 3 | 0.629 |
NIPA1 | CNNM1 | ENSP00000337452 | ENSP00000349147 | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | cyclin M1; Probable metal transporter (By similarity) | 0.491 |
NIPA1 | CNNM2 | ENSP00000337452 | ENSP00000358894 | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | 0.488 |