Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
CNNM2 CNNM2 MRS2 MRS2 MMGT1 MMGT1 NIPA1 NIPA1 CNNM1 CNNM1 PDZD3 PDZD3 SLC41A3 SLC41A3 SLC35A4 SLC35A4 CHST13 CHST13 RIMS2 RIMS2 CHST11 CHST11
"SLC41A3" - solute carrier family 41, member 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC41A3solute carrier family 41, member 3 (507 aa)    
Predicted Functional Partners:
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan (341 aa)
            score_image   0.680
SLC35A4
solute carrier family 35, member A4 (324 aa)
            score_image   0.635
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix (443 aa)
            score_image   0.629
MMGT1
membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) (131 aa)
            score_image   0.621
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) (329 aa)
            score_image   0.596
PDZD3
PDZ domain containing 3; Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions (505 aa)
        score_image   score_image   0.592
RIMS2
regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein (1349 aa)
            score_image   0.583
CNNM2
cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) (875 aa)
            score_image   0.491
CNNM1
cyclin M1; Probable metal transporter (By similarity) (951 aa)
            score_image   0.483
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor (352 aa)
            score_image   0.483
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (41%)