Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | GANC | glucosidase, alpha; neutral C; Has alpha-glucosidase activity (914 aa) | ||||||||||||
Predicted Functional Partners:
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 | AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (1532 aa) |
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0.928 | |||||||||
 | HK3 | hexokinase 3 (white cell) (923 aa) |
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0.927 | |||||||||
 | SI | sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides (1827 aa) |
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0.925 | ||||||||
 | KLRP | glucosidase, beta, acid 3 (cytosolic) (EC-3.2.1.21) (162 aa) |
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0.923 | |||||||||
 | HK1 | hexokinase 1 (921 aa) |
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0.923 | |||||||||
 | HK2 | hexokinase 2 (917 aa) |
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0.922 | |||||||||
 | PRKCSH | protein kinase C substrate 80K-H; Regulatory subunit of glucosidase II (528 aa) |
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0.919 | |||||||||
 | MOGS | mannosyl-oligosaccharide glucosidase; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner (837 aa) |
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0.906 | |||||||||
 | HKDC1 | hexokinase domain containing 1 (917 aa) |
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0.900 | ||||||||||
 | GNPTG | N-acetylglucosamine-1-phosphate transferase, gamma subunit; May recognize the substrate of GlcNAc-1- phosphotransferase but also the lysosomal proteins with mannose-6- phosphate residues (305 aa) |
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0.869 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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