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STRINGSTRING
ACADVL ACADVL ACAD9 ACAD9 DBR1 DBR1 UBC UBC XRCC6BP1 XRCC6BP1 CWF19L1 CWF19L1 SS18L1 SS18L1 PRPF19 PRPF19 BUD31 BUD31 NXPE3 NXPE3 CDC40 CDC40
"CWF19L1" - CWF19-like 1, cell cycle control (S. pombe) in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CWF19L1CWF19-like 1, cell cycle control (S. pombe) (538 aa)    
Predicted Functional Partners:
DBR1
debranching enzyme homolog 1 (S. cerevisiae); Cleaves the 2’-5’ phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via a RNA lariat intermediate in cDNA synthesis (544 aa)
        score_image   score_image score_image 0.898
UBC
ubiquitin C (685 aa)
        score_image       0.849
BUD31
BUD31 homolog (S. cerevisiae) (144 aa)
        score_image       0.827
CDC40
cell division cycle 40 homolog (S. cerevisiae); Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing (579 aa)
        score_image       0.805
PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae); Plays a role in DNA double-strand break (DSB) repair. Binds double-stranded DNA in a sequence-nonspecific manner. Acts as a structural component of the nuclear framework. May also serve as a support for spliceosome binding and activity. Essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. May have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Component of the PRP19-CDC5L comple [...] (504 aa)
      score_image score_image       0.744
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1 (396 aa)
            score_image   0.731
NXPE3
neurexophilin and PC-esterase domain family, member 3 (559 aa)
            score_image   0.710
ACAD9
acyl-CoA dehydrogenase family, member 9; Has a dehydrogenase activity on palmitoyl-CoA (C16-0) and stearoyl-CoA (C18-0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. Has little activity on octanoyl-CoA (C8-0), butyryl-CoA (C4-0) or isovaleryl-CoA (5-0) (621 aa)
            score_image   0.704
ACADVL
acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons (655 aa)
            score_image   0.564
XRCC6BP1
XRCC6 binding protein 1 (246 aa)
            score_image   0.522
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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