SLC25A42 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SLC25A42

solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate (318 aa)

Predicted Functional Partners:

WDR47

0.599

SLC25A34

0.586

SLC25A35

0.499

FAM171A2

0.477

NUDT19

0.471

CDYL2

0.469

SLC25A48

0.429

NUDT7

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDYL2	FAM171A2	ENSP00000299564	ENSP00000293443	chromodomain protein, Y-like 2	family with sequence similarity 171, member A2	0.402
CDYL2	SLC25A42	ENSP00000299564	ENSP00000326693	chromodomain protein, Y-like 2	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.469
FAM171A2	CDYL2	ENSP00000293443	ENSP00000299564	family with sequence similarity 171, member A2	chromodomain protein, Y-like 2	0.402
FAM171A2	SLC25A42	ENSP00000293443	ENSP00000326693	family with sequence similarity 171, member A2	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.477
NUDT19	NUDT7	ENSP00000380251	ENSP00000268533	nudix (nucleoside diphosphate linked moiety X)-type motif 19; Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity)	nudix (nucleoside diphosphate linked moiety X)-type motif 7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3’,5’-ADP and the corresponding 4’-phosphopantetheine derivative as products. CoA into 3’,5’-ADP and 4’- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5’-triphosphates, nucleoside 5’-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5’-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, [...]	0.509
NUDT19	SLC25A42	ENSP00000380251	ENSP00000326693	nudix (nucleoside diphosphate linked moiety X)-type motif 19; Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity)	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.471
NUDT7	NUDT19	ENSP00000268533	ENSP00000380251	nudix (nucleoside diphosphate linked moiety X)-type motif 7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3’,5’-ADP and the corresponding 4’-phosphopantetheine derivative as products. CoA into 3’,5’-ADP and 4’- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5’-triphosphates, nucleoside 5’-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5’-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, [...]	nudix (nucleoside diphosphate linked moiety X)-type motif 19; Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity)	0.509
NUDT7	SLC25A42	ENSP00000268533	ENSP00000326693	nudix (nucleoside diphosphate linked moiety X)-type motif 7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3’,5’-ADP and the corresponding 4’-phosphopantetheine derivative as products. CoA into 3’,5’-ADP and 4’- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5’-triphosphates, nucleoside 5’-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5’-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, [...]	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.414
SLC25A34	SLC25A42	ENSP00000294454	ENSP00000326693	solute carrier family 25, member 34	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.586
SLC25A35	SLC25A42	ENSP00000369407	ENSP00000326693	solute carrier family 25, member 35	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.499
SLC25A42	CDYL2	ENSP00000326693	ENSP00000299564	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	chromodomain protein, Y-like 2	0.469
SLC25A42	FAM171A2	ENSP00000326693	ENSP00000293443	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	family with sequence similarity 171, member A2	0.477
SLC25A42	NUDT19	ENSP00000326693	ENSP00000380251	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	nudix (nucleoside diphosphate linked moiety X)-type motif 19; Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity)	0.471
SLC25A42	NUDT7	ENSP00000326693	ENSP00000268533	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	nudix (nucleoside diphosphate linked moiety X)-type motif 7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3’,5’-ADP and the corresponding 4’-phosphopantetheine derivative as products. CoA into 3’,5’-ADP and 4’- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5’-triphosphates, nucleoside 5’-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5’-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, [...]	0.414
SLC25A42	SLC25A34	ENSP00000326693	ENSP00000294454	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	solute carrier family 25, member 34	0.586
SLC25A42	SLC25A35	ENSP00000326693	ENSP00000369407	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	solute carrier family 25, member 35	0.499
SLC25A42	SLC25A48	ENSP00000326693	ENSP00000413049	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	solute carrier family 25, member 48	0.429
SLC25A42	WDR47	ENSP00000326693	ENSP00000383599	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	WD repeat domain 47	0.599
SLC25A48	SLC25A42	ENSP00000413049	ENSP00000326693	solute carrier family 25, member 48	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.429
WDR47	SLC25A42	ENSP00000383599	ENSP00000326693	WD repeat domain 47	solute carrier family 25, member 42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate	0.599

Textmining

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About