node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAD | SLC35A4 | ENSP00000264705 | ENSP00000327133 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | solute carrier family 35, member A4 | 0.495 |
CERS6 | SLC35A4 | ENSP00000306579 | ENSP00000327133 | ceramide synthase 6; May be involved in sphingolipid synthesis or its regulation (By similarity) | solute carrier family 35, member A4 | 0.511 |
SLC27A4 | SLC35A4 | ENSP00000300456 | ENSP00000327133 | solute carrier family 27 (fatty acid transporter), member 4; Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity) | solute carrier family 35, member A4 | 0.488 |
SLC27A4 | SLC41A3 | ENSP00000300456 | ENSP00000326070 | solute carrier family 27 (fatty acid transporter), member 4; Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity) | solute carrier family 41, member 3 | 0.441 |
SLC35A4 | CAD | ENSP00000327133 | ENSP00000264705 | solute carrier family 35, member A4 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.495 |
SLC35A4 | CERS6 | ENSP00000327133 | ENSP00000306579 | solute carrier family 35, member A4 | ceramide synthase 6; May be involved in sphingolipid synthesis or its regulation (By similarity) | 0.511 |
SLC35A4 | SLC27A4 | ENSP00000327133 | ENSP00000300456 | solute carrier family 35, member A4 | solute carrier family 27 (fatty acid transporter), member 4; Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity) | 0.488 |
SLC35A4 | SLC35B4 | ENSP00000327133 | ENSP00000367770 | solute carrier family 35, member A4 | solute carrier family 35, member B4; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi | 0.476 |
SLC35A4 | SLC35C1 | ENSP00000327133 | ENSP00000313318 | solute carrier family 35, member A4 | solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen | 0.491 |
SLC35A4 | SLC35D2 | ENSP00000327133 | ENSP00000253270 | solute carrier family 35, member A4 | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | 0.517 |
SLC35A4 | SLC35E2B | ENSP00000327133 | ENSP00000234800 | solute carrier family 35, member A4 | solute carrier family 35, member E2B; Putative transporter (By similarity) | 0.536 |
SLC35A4 | SLC35E4 | ENSP00000327133 | ENSP00000339626 | solute carrier family 35, member A4 | solute carrier family 35, member E4; Putative transporter (By similarity) | 0.485 |
SLC35A4 | SLC41A3 | ENSP00000327133 | ENSP00000326070 | solute carrier family 35, member A4 | solute carrier family 41, member 3 | 0.635 |
SLC35A4 | SLC6A15 | ENSP00000327133 | ENSP00000266682 | solute carrier family 35, member A4 | solute carrier family 6 (neutral amino acid transporter), member 15; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent | 0.473 |
SLC35B4 | SLC35A4 | ENSP00000367770 | ENSP00000327133 | solute carrier family 35, member B4; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi | solute carrier family 35, member A4 | 0.476 |
SLC35B4 | SLC35C1 | ENSP00000367770 | ENSP00000313318 | solute carrier family 35, member B4; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi | solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen | 0.540 |
SLC35B4 | SLC35D2 | ENSP00000367770 | ENSP00000253270 | solute carrier family 35, member B4; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | 0.504 |
SLC35C1 | SLC35A4 | ENSP00000313318 | ENSP00000327133 | solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen | solute carrier family 35, member A4 | 0.491 |
SLC35C1 | SLC35B4 | ENSP00000313318 | ENSP00000367770 | solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen | solute carrier family 35, member B4; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi | 0.540 |
SLC35C1 | SLC35D2 | ENSP00000313318 | ENSP00000253270 | solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | 0.879 |